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Restless legs syndrome (RLS), (also known as Willis–Ekbom disease (WED), is a neurological disorder, usually chronic, that causes an overwhelming urge to move one's legs. [ 2 ] [ 10 ] There is often an unpleasant feeling in the legs that improves temporarily by moving them. [ 2 ]
Activation of trigger points may be caused by a number of factors, including acute or chronic muscle overload, activation by other trigger points (key/satellite, primary/secondary), disease, psychological distress (via systemic inflammation), homeostatic imbalances, direct trauma to the region, collision trauma (such as a car crash which stresses many muscles and causes instant trigger points ...
Cardiac muscle. There are few studies corroborating the effectiveness of exercise for limb–girdle muscular dystrophy. However studies have shown that exercise can, in fact, damage muscles permanently due to intense muscle contraction. [24] Physical therapy may be required to maintain as much muscle strength and joint flexibility as possible.
Symptoms of neuromuscular disease may include numbness, paresthesia, muscle atrophy, a pseudoathletic appearance, exercise intolerance, myalgia (muscle pain), fasciculations (muscle twitches), myotonia (delayed muscle relaxation), hypotonia (lack of resistance to passive movement), fixed muscle weakness (a static symptom), or premature muscle ...
Some studies have shown a reasonably characteristic pattern of muscle involvement on whole-body muscle MRI in LAMA2-MD patients. [19] [20] This relates to muscles or group of muscles involvement versus sparing. For example, sparing of the gracilis, sartorius muscles, [20] and the adductor longus muscle [19] [21] has been linked to LAMA2-MD.
Progress on treating stiff-person syndrome has been slow, Claudette noted, being that it is rare. "The vocal cords are muscles, and the heart is also a muscle," said Claudette.
Physical therapy involves training the use of the affected limb or training the use of the body. This is for the purpose of retraining muscles after muscle atrophy, and retraining how to use the affected muscles with less amplified pain. Massage therapy is used to desensitize the affected area or body so it can build a tolerance to pain.
Milder forms present with symptoms other than weakness, such as muscle aches, cramps, or exercise intolerance, and people in this group can retain ambulation beyond age 60. [3] Weakness is symmetric, progressive, and proximal (on or close to the torso), usually affecting the hip girdle and shoulder girdle muscles.