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HATU is commonly encountered in amine acylation reactions (i.e., amide formation). Such reactions are typically performed in two distinct reaction steps: (1) reaction of a carboxylic acid with HATU to form the OAt-active ester; then (2) addition of the nucleophile (amine) to the active ester solution to afford the acylated product.
The following compounds are liquid at room temperature and are completely miscible with water; they are often used as solvents. Many of them are hygroscopic.
An example in liquids is the miscibility of water and ethanol as they mix in all proportions. [1] By contrast, substances are said to be immiscible if the mixture does not form a solution for certain proportions. For one example, oil is not soluble in water, so these two solvents are immiscible
For example, a solution of table salt, also known as sodium chloride (NaCl), in water would be represented as Na + (aq) + Cl − (aq). The word aqueous (which comes from aqua) means pertaining to, related to, similar to, or dissolved in, water. [1] [2] As water is an excellent solvent and is also naturally abundant, it is a ubiquitous solvent ...
The following chart shows the solubility of various ionic compounds in water at 1 atm pressure and room temperature (approx. 25 °C, 298.15 K). "Soluble" means the ionic compound doesn't precipitate, while "slightly soluble" and "insoluble" mean that a solid will precipitate; "slightly soluble" compounds like calcium sulfate may require heat to precipitate.
The solubility of a specific solute in a specific solvent is generally expressed as the concentration of a saturated solution of the two. [1] Any of the several ways of expressing concentration of solutions can be used, such as the mass, volume, or amount in moles of the solute for a specific mass, volume, or mole amount of the solvent or of the solution.
Making a saline water solution by dissolving table salt in water.The salt is the solute and the water the solvent. In chemistry, a solution is defined by IUPAC as "A liquid or solid phase containing more than one substance, when for convenience one (or more) substance, which is called the solvent, is treated differently from the other substances, which are called solutes.
1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC, EDAC or EDCI) is a water-soluble carbodiimide usually handled as the hydrochloride. [1] It is typically employed in the 4.0-6.0 pH range. It is generally used as a carboxyl activating agent for the coupling of primary amines to yield amide bonds.