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A patch test relies on the principle of a type IV hypersensitivity reaction.. The first step in becoming allergic is sensitization. When skin is exposed to an allergen, the antigen-presenting cells (APCs) – also known as Langerhans cell or Dermal Dendritic Cell – phagocytize the substance, break it down to smaller components and present them on their surface bound major histocompatibility ...
Patch test: applying a patch to the skin, where the patch contains the allergen; If an immuno-response is seen in the form of a rash, urticaria , or anaphylaxis it can be concluded that the patient has a hypersensitivity (or allergy) to that allergen. Further testing can be done to identify the particular allergen. [citation needed]
A broader definition of patch test (applicable to any numerical method, including and beyond finite elements) is any test problem having an exact solution that can, in principle, be exactly reproduced by the numerical approximation. Therefore, a finite-element simulation that uses linear shape functions has patch tests for which the exact ...
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The Schick test, developed in 1913, [1] is a skin test used to determine whether or not a person is susceptible to diphtheria. [2] It was named after its inventor, Béla Schick (1877–1967), a Hungarian-born American pediatrician.
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