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Epinephrine nasal spray also demonstrated similar increases in blood pressure and heart rate as epinephrine injection products, two critical effects of epinephrine in the treatment of anaphylaxis. [30] A study of epinephrine nasal spray in children weighing more than 66 pounds showed that epinephrine concentrations in children were similar to ...
An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.
Anaphylaxis can occur in response to almost any foreign substance. [20] Common triggers include venom from insect bites or stings, foods, and medication. [10] [21] Foods are the most common trigger in children and young adults, while medications and insect bites and stings are more common in older adults. [3]
Epinephrine autoinjectors are portable single-dose epinephrine-dispensing devices used to treat anaphylaxis. Epinephrine (adrenaline) is the first-line treatment for severe allergic reactions (anaphylaxis). If administered in a timely manner, epinephrine can reverse its effects. Epinephrine relieves airway swelling and obstruction, and improves ...
IRL anaphylaxis runs about a 1 in 5 chance of being biphasic and a 1 in 10 chance of needing an overnight hospital stay. Even when no complications develop, anaphylaxis is fatiguing.
The mechanisms of sympathomimetic drugs can be direct-acting (direct interaction between drug and receptor), such as α-adrenergic agonists, β-adrenergic agonists, and dopaminergic agonists; or indirect-acting (interaction not between drug and receptor), such as MAOIs, COMT inhibitors, release stimulants, and reuptake inhibitors that increase the levels of endogenous catecholamines.
Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [10] [12] It appears as a white microcrystalline granule. [13] Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. [14]
Epinephrine autoinjectors are portable single-dose epinephrine-dispensing devices used to treat anaphylaxis. Treatment for accidental ingestion of soy products by allergic individuals varies depending on the sensitivity of the person. An antihistamine such as diphenhydramine (Benadryl) may be prescribed. [1]