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Crisaborole was approved for use in the United States in December 2016 [14] [1] and for use in Canada in June 2018. [15] The safety and efficacy of crisaborole were established in two placebo-controlled trials with a total of 1,522 participants ranging in age from two years of age to 79 years of age, with mild to moderate atopic dermatitis. [1]
Oclacitinib, sold under the brand name Apoquel among others, is a veterinary medication used in the control of atopic dermatitis and pruritus from allergic dermatitis in dogs at least 12 months of age. [1] [4] Chemically, it is a synthetic cyclohexylamino pyrrolopyrimidine janus kinase inhibitor that is relatively selective for JAK1. [5]
Pentoxifylline has been tested for use in sarcoidosis patients as an alternative or compliment to prednisone and other steroids, as the drug can inhibit excess levels of TNF-a, which is associated with granuloma formation. [9] [10] [11] It has further been used to treat immunologic reactions to leprosy with some success. [12]
Apoquel is an FDA-approved medication used to provide relief for dogs suffering from itching and inflammation associated with allergic dermatitis and atopic dermatitis. It is the brand name for ...
Here are links to possibly useful sources of information about Crisaborole. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC
Uses [ edit ] Propentofylline was studied as a possible treatment for Alzheimer's disease and multi-infarct dementia , [ 1 ] [ 4 ] and has been studied, to a lesser extent, as a possible adjunct in the treatment of ischemic stroke , due to its vasodilating properties.
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