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  2. H1N1 vaccines - World Health Organization (WHO)

    www.who.int/.../topics/influenza-vaccines/h1n1-vaccines

    Immediate hypersensitivity reactions have been reported after the use of all types of pandemic (H1N1) 2009 vaccines. These events include urticaria, angioedema and anaphylaxis, with reactions ranging from mild to serious. The overall reporting rates for anaphylaxis range from 0.1 to 1.0 per 100 000 doses distributed.

  3. History of influenza vaccination - World Health Organization...

    www.who.int/news-room/spotlight/history-of-vaccination/history-of-influenza...

    A live attenuated vaccine delivered in the form of a nasal spray was first licensed in 2003, a vaccine using recombinant DNA technology was approved in 2013, and additional influenza vaccines based on newer technologies are being tested in clinical trials. Despite these efforts, seasonal influenza still kills up to 650 000 people a year globally.

  4. Pandemic influenza vaccine manufacturing process and timeline

    www.who.int/news/item/06-08-2009-pandemic-influenza-vaccine-manufacturing...

    It takes approximately five to six months for the first supplies of approved vaccine to become available once a new strain of influenza virus with pandemic potential is identified and isolated. These months are needed because the process of producing a new vaccine involves many sequential steps, and each of these steps requires a certain amount of time to complete. The vaccine development ...

  5. Recommendations announced for influenza vaccine composition for...

    www.who.int/news/item/24-02-2023-recommendations-announced-for-influenza...

    The recommendations issued are used by the national vaccine regulatory agencies and pharmaceutical companies to develop, produce, and license influenza vaccines for the following influenza season. The periodic update of viruses contained in influenza vaccines is necessary for the vaccines to be effective due to the constant evolving nature of ...

  6. Influenza A H1N1 variant virus - Brazil - World Health...

    www.who.int/emergencies/disease-outbreak-news/item/2023-DON473

    On 7 June 2023, Brazil notified the World Health Organization (WHO) of a fatal laboratory-confirmed human case of infection with a swine-origin influenza A(H1N1) variant (v) virus in the inner state of Paraná. Sporadic human cases of influenza A(H1N1)v have been reported previously, including from Brazil. According to the International Health Regulations (IHR) 2005, a human infection caused ...

  7. Influenza A (H1N1) outbreak - World Health Organization (WHO)

    www.who.int/emergencies/situations/influenza-a-(h1n1)-outbreak

    Overview. Before the H1N1 pandemic in 2009, the influenza A (H1N1) virus had never been identified as a cause of infections in people. Genetic analyses of this virus have shown that it originated from animal influenza viruses and is unrelated to the human seasonal H1N1 viruses that have been in general circulation among people since 1977.

  8. Recommendations announced for influenza vaccine composition for...

    www.who.int/news/item/23-02-2024-recommendations-announced-for-influenza...

    The World Health Organization (WHO) today announced the recommendations for the viral composition of influenza vaccines for the 2024-2025 influenza season in the northern hemisphere. The announcement was made at an information session after a 4-day meeting on the Composition of Influenza Virus Vaccines. The meeting is held twice annually, once for the southern and once for the northern ...

  9. Candidate vaccine viruses and potency testing reagents

    www.who.int/teams/global-influenza-programme/vaccines/who-recommendations/...

    Global Influenza Programme. We provide Member States with strategic guidance, technical support and coordination of activities essential to make their health systems better prepared against seasonal, zoonotic and pandemic influenza threats to populations and individuals. About.

  10. Report of the WHO Pandemic Influenza A(H1N1) Vaccine Deployment...

    www.who.int/publications/i/item/report-of-the-who-pandemic-influenza-a(h1n1...

    In June, the 2009 H1N1 influenza pandemic was declared. Under the mandate of the International Health Regulations (IHR; 2005) the Director-General of WHO convened a technical Emergency Committee to assess the situation and to advise on the most appropriate actions to take. As part of this, and to ensure that developing countries were able to ...

  11. Influenza A (H1N1) variant virus - the Netherlands

    www.who.int/emergencies/disease-outbreak-news/item/2023-DON486

    On 2 September 2023, the Ministry of Health, Welfare and Sport of the Netherlands notified the World Health Organization (WHO) of a laboratory-confirmed human case of infection with a swine-origin influenza A(H1N1) variant (v) virus in the province of North Brabant, Netherlands. This is the first human infection caused by influenza A(H1N1)v virus reported in the Netherlands in 2023. Worldwide ...