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The focus of translational neuroscience research is to investigate the molecular mechanisms for these disorders, and to investigate the mechanisms of drug delivery to treat these disorders, including an investigation into the impact of the blood-brain barrier on drug delivery, and the role of the body's immune system in neurodegenerative disorders.
Karen Faith Berman is an American psychiatrist and physician-scientist who is a senior investigator and chief of the section on integrative neuroimaging, the psychosis and cognitive studies section, and the clinical and translational neuroscience branch of the National Institute of Mental Health's division of intramural research.
In bioscience, translational research is a term often used interchangeably with translational medicine or translational science or bench to bedside. The adjective "translational" refers to the " translation " (the term derives from the Latin for "carrying over") of basic scientific findings in a laboratory setting into potential treatments for ...
The Journal of Neural Transmission is a monthly peer-reviewed medical journal covering clinical neurology and translational neuroscience. It was established in 1950 by Carmen Coronini and Alexander Sturm as Acta Neurovegetativa. [1] It was renamed to the Journal of Neuro-Visceral Relations in 1968 and to its current title in 1972.
Transcranial random noise stimulation (tRNS) is a non-invasive brain stimulation technique and a form of transcranial electrical stimulation (tES). Terney et al from Göttingen University was the first group to apply tRNS in humans in 2008.
In certain cases one of these steps (i.e., nuclear import or nuclear export) is regulated, often by post-translational modifications. Nuclear import limits the propagation of large proteins expressed in skeletal muscle fibers and possibly other syncytial tissues, maintaining localized gene expression in certain nuclei. [ 7 ]
Neuromodulation is the physiological process by which a given neuron uses one or more chemicals to regulate diverse populations of neurons. Neuromodulators typically bind to metabotropic, G-protein coupled receptors (GPCRs) to initiate a second messenger signaling cascade that induces a broad, long-lasting signal.
Lesné holds a master's degree in biochemistry and has a PhD with a major in neuroscience from the University of Caen Normandy. [9] His doctoral thesis (2002) was "Régulation d'expression et du métabolisme d'APP au cours des pathologies dégénératives" (Regulation of APP expression and metabolism during degenerative pathologies). [10]