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Ancylostoma caninum is a species of nematode known as a hookworm, which principally infects the small intestine of dogs. [1] [2] [3] The result of A. caninum infection ranges from asymptomatic cases to death of the dog; better nourishment, increasing age, prior A. caninum exposure, or vaccination are all linked to improved survival.
Side effects can include gastrointestinal, esophageal or neurological issues, liver and kidney damage or allergic reactions of varying severity. Antibiotics can be crucial in treating pets. But ...
For treatment against roundworms, drugs based on emodepside, fenbendazole, flubendazole, mebendazole, milbemycin oxime, moxidectin, pyrantel and selamectin are approved in Germany for domestic dogs. These drugs are broad-spectrum anthelmintics and also exert activity against most other nematodes found in dogs. [70]
Hookworms infected about 428 million people in 2015. [4] Heavy infections can occur in both children and adults, but are less common in adults. [2] They are rarely fatal. [6] Hookworm infection is a soil-transmitted helminthiasis and classified as a neglected tropical disease. [7]
Hookworm is closely associated with poverty because it is most often found in impoverished areas, and its symptoms promote poverty through the educational and health effects it has on children. [2] It is the leading cause of anemia and undernutrition in developing countries, while being one of the most commonly occurring diseases among poor ...
Moxidectin was approved for onchocerciasis (river-blindness) in 2018 for people over the age of 11 in the United States based on two studies. [5] There is a need for additional trials, with long-term follow-up, to assess whether moxidectin is safe and effective for treatment of nematode infection in children and women of childbearing potential. [6]