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Research regarding late-life depression often focuses on late-onset depression, which is defined as a major depressive episode occurring for the first time in an older person (various sources define this threshold differently, typically within the range of 60–65 years old). [1] [2] Late-life depression is often underdiagnosed, which is due to ...
Poor sleep can lead to the development of depression, and depression can cause insomnia, hypersomnia, or obstructive sleep apnea. [58] [59] About 75% of adult patients with depression can present with insomnia. [60]
In their lifetime, 20% to 25% of women and 7% to 12% of men will have a major depressive episode. [35] The peak period of development is between the ages of 25 and 44. [3] The onset of major depressive episodes or MDD often occurs in people in their mid-20s and less often in those over 65.
(Reuters) -Johnson & Johnson's experimental drug helped reduce symptoms of depression as well as insomnia in patients with major depressive disorder (MDD) in a late-stage trial, the company said ...
If PKA or protein synthesis inhibition occurs at certain moments during sleep, memory consolidation can be disrupted [citation needed]. In addition, mice with genetic inhibition of PKA have been shown to have long-term memory deficits. [48] Thus, sleep deprivation may act through the inhibition of these protein synthesis pathways.
This article needs to be updated. The reason given is: Many outdated sources and information (older than five years). Please help update this article to reflect recent events or newly available information. (July 2024) Medical condition Major depressive disorder Other names Clinical depression, major depression, unipolar depression, unipolar disorder, recurrent depression Sorrowing Old Man (At ...
Family history, previous diagnosis of a mood disorder, trauma, stress or major life changes in the case of depression, physical illness or use of certain medications. Depression has been linked to major diseases such as cancer, diabetes, Parkinson's disease and heart disease, Brain structure and function in the case of bipolar disorder. [1 ...
A large sleep debt may lead to mental or physical fatigue, and can adversely affect one's mood, energy, and ability to think clearly. There are two kinds of sleep debt: the result of partial sleep deprivation, and of total sleep deprivation. Partial sleep deprivation occurs when a person or a lab animal sleeps too little for several days or ...
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