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  2. Chronic lymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Chronic_lymphocytic_leukemia

    Chronic lymphocytic leukemia (CLL) is a type of cancer that affects the blood and bone marrow. [8] [9] In CLL, the bone marrow makes too many lymphocytes, which are a type of white blood cell. [8] [9] In patients with CLL, B cell lymphocytes can begin to collect in their blood, spleen, lymph nodes, and bone marrow.

  3. Venetoclax - Wikipedia

    en.wikipedia.org/wiki/Venetoclax

    Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL), or acute myeloid leukemia (AML).

  4. List of drugs granted breakthrough therapy designation

    en.wikipedia.org/wiki/List_of_drugs_granted...

    Drug Manufacturer Indication Ivacaftor [1] Vertex Pharmaceuticals: cystic fibrosis with CFTR mutation Ofatumumab [1] Novartis Pharmaceuticals: chronic lymphocytic leukemia: Ceritinib [1] Novartis Pharmaceuticals: ALK-positive metastatic non-small cell lung cancer: Idelalisib [1] Gilead Sciences: relapsed chronic lymphocytic leukemia: Ibrutinib ...

  5. Rituximab - Wikipedia

    en.wikipedia.org/wiki/Rituximab

    Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...

  6. Fludarabine - Wikipedia

    en.wikipedia.org/wiki/Fludarabine

    It is a chemotherapy medication used in the treatment of leukemia and lymphoma. [3] These include chronic lymphocytic leukemia, non-Hodgkin's lymphoma, acute myeloid leukemia, and acute lymphocytic leukemia. [3] It is given by injection into a vein or by mouth. [3]

  7. List of antineoplastic agents - Wikipedia

    en.wikipedia.org/wiki/List_of_antineoplastic_agents

    Chronic lymphocytic leukaemia, mantle cell lymphoma and non-Hodgkin's lymphoma. Myelosuppression, hypokalaemia and tachycardia. Busulfan: IV, PO: Alkylates DNA. Conditioning treatment before haematopoietic stem cell transplantation (high dose, IV), chronic myeloid leukaemia, myelofibrosis, polycythaemia vera and essential thrombocytosis

  8. Ofatumumab - Wikipedia

    en.wikipedia.org/wiki/Ofatumumab

    Ofatumumab (Arzerra 100 mg or 1000 mg concentrate for solution for infusion) is indicated for the treatment of untreated, relapsed, or refractory chronic lymphocytic leukemia (CLL). [ 8 ] [ 20 ] [ 6 ] [ 21 ] The recommended doses for treatment of CLL are higher than MS, with 1000 or 2000 mg infusions administered monthly depending on if the CLL ...

  9. List of antileukemic drugs - Wikipedia

    en.wikipedia.org/wiki/List_of_antileukemic_drugs

    Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include: [1] 6-Mercaptopurine; 6-Thioguanine; Arsenic trioxide; Asparaginase;

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