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Increase the risk of hypoglycemia; Glyburide increases risk of hypoglycemia slightly more compared to glimepiride and glipizide; Metformin: Acts on the liver to reduce gluconeogenesis and causes a decrease in insulin resistance via increasing AMPK signalling. Associated with weight loss; Lower risk of hypoglycemia compared to other antidiabetics
In addition to helping people with diabetes manage their blood sugar levels, this GLP-1 (glucagon-like peptide 1 receptor agonist) medication helps reduce appetite and curb food cravings.
This often translates into highly processed food, including grab-and-go snacks like potato chips, canned foods including soups and a lot found in drive-thrus or frozen aisles in the grocery store.
Glimepiride is an antidiabetic medication within the sulfonylurea class, primarily prescribed for the management of type 2 diabetes. [ 1 ] [ 2 ] It is regarded as a second-line option compared to metformin , due to metformin's well-established safety and efficacy. [ 1 ]
Fiber-rich foods naturally slow digestion. “Fiber-rich foods reduce food noise by adding bulk to your meals without extra calories and slowing digestion, which helps control hunger,” Mohr says ...
They are also a first-line treatment for people with both type 2 diabetes and kidney disease. Both types of medication can be combined with metformin . [ 8 ] [ 9 ] One advantage of GLP-1 agonists over older insulin secretagogues , such as sulfonylureas or meglitinides , is that they have a lower risk of causing hypoglycemia . [ 10 ]
In patients with diabetes mellitus type 1, alpha-glucosidase inhibitors use has not been officially approved by the Food and Drug Administration in the US but some data exists on the effectiveness in this population, showing potential benefits weighted against an increased risk of hypoglycemia. [18]
Glipizide, sold under the brand name Glucotrol among others, is an anti-diabetic medication of the sulfonylurea class used to treat type 2 diabetes. [1] [2] It is used together with a diabetic diet and exercise. [1] [2] It is not indicated for use by itself in type 1 diabetes. [1] [2] It is taken by mouth.