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Valve replacement surgery is the replacement of one or more of the heart valves with either an artificial heart valve or a bioprosthesis (homograft from human tissue or xenograft e.g. from pig). It is an alternative to valve repair .
Decellularization of porcine heart valves is the removal of cells along with antigenic cellular elements [1] by either physical or chemical decellularization of the tissue. [2] This decellularized valve tissue provides a scaffold with the remaining extracellular matrix (ECM) that can then be used for tissue engineering and valve replacement in ...
The Hancock Aortic Tissue Valve is a prosthetic heart valve used in cardiac surgery to replace a damaged or diseased aortic valve. [1] It is a bioprosthetic valve, meaning it is constructed using biological tissues, specifically porcine (pig) valve tissue. [ 2 ]
An aortic homograft is an aortic valve from a human donor, retrieved either after their death or from a heart that is removed to be replaced during a heart transplant. [12] A pulmonary autograft, also known as the Ross procedure , is where the aortic valve is removed and replaced with the patient's own pulmonary valve (the valve between the ...
The shape of these valves do not mimic normal heart valves. Tissue heart valves are usually made from animal tissues, either animal heart valve tissue or animal pericardial tissue, commonly from the pig. The tissue is pretreated by removing antigens to prevent rejection and to prevent calcification. These valves tend to model after normal ...
A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Heart valves are opened or closed by a difference in blood pressure on each side. [1] [2] [3]
Aortic valve replacement is a cardiac surgery procedure whereby a failing aortic valve is replaced with an artificial heart valve. The aortic valve may need to be replaced because of aortic regurgitation (back flow), or if the valve is narrowed by stenosis .
Diagram of the human heart. Several adaptations of the Ross procedure have evolved, but the principle is essentially the same; to replace a diseased aortic valve with the person's own pulmonary valve (autograft), and replace the person's own pulmonary valve with a pulmonary valve from a cadaver (homograft) or a stentless xenograft.