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Life is a 2017 American science fiction horror film [5] [6] [7] directed by Daniel Espinosa, written by Rhett Reese and Paul Wernick and starring an ensemble cast consisting of Jake Gyllenhaal, Rebecca Ferguson, Ryan Reynolds, Hiroyuki Sanada, Ariyon Bakare, and Olga Dihovichnaya.
RNA-dependent DNA polymerases are a specialized class of polymerases that copy the sequence of an RNA strand into DNA. They include reverse transcriptase , which is a viral enzyme involved in the infection of cells by retroviruses , and telomerase , which is required for the replication of telomeres.
While the sugar-phosphate "backbone" of DNA contains deoxyribose, RNA contains ribose instead. [6] Ribose has a hydroxyl group attached to the pentose ring in the 2' position, whereas deoxyribose does not. The hydroxyl groups in the ribose backbone make RNA more chemically labile than DNA by lowering the activation energy of hydrolysis.
In contrast, DNA Pol I is the enzyme responsible for replacing RNA primers with DNA. DNA Pol I has a 5′ to 3′ exonuclease activity in addition to its polymerase activity, and uses its exonuclease activity to degrade the RNA primers ahead of it as it extends the DNA strand behind it, in a process called nick translation. Pol I is much less ...
Life is a 2015 biographical drama film directed by Anton Corbijn and written by Luke Davies. It is based on the friendship of Life photographer Dennis Stock and American actor James Dean , starring Robert Pattinson as Stock and Dane DeHaan as Dean.
Life Story (known as The Race for the Double Helix in the United States) is a 1987 television historical drama which depicts the progress toward, and the competition for, the discovery of the structure of DNA in the early 1950s.
Many viruses replicate this way. The enzymes that copy RNA to new RNA, called RNA-dependent RNA polymerases, are also found in many eukaryotes where they are involved in RNA silencing. [11] RNA editing, in which an RNA sequence is altered by a complex of proteins and a "guide RNA", could also be seen as an RNA-to-RNA transfer.
A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription.Reverse transcriptases are used by viruses such as HIV and hepatitis B to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the host genome, and by eukaryotic cells to extend the telomeres at the ends of their linear chromosomes.