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Cocaine and amphetamine regulated transcript. Cocaine- and amphetamine-regulated transcript, also known as CART, is a neuropeptide protein that in humans is encoded by the CARTPT gene. [ 1 ][ 2 ] CART appears to have roles in reward, feeding, and stress, [ 3 ] and it has the functional properties of an endogenous psychostimulant. [ 4 ]
Stimulant use disorder is a type of substance use disorder where the use of stimulants caused clinically significant impairment or distress. It is defined in the DSM-5 as "the continued use of amphetamine-type substances, cocaine, or other stimulants leading to clinically significant impairment or distress, from mild to severe". [1]
Stimulant. Ritalin: 20 mg sustained-release (SR) tablets. Stimulants (also known as central nervous system stimulants, or psychostimulants, or colloquially as uppers) are a class of drugs that increase the activity of the brain. They are used for various purposes, such as enhancing alertness, attention, motivation, cognition, mood, and physical ...
Amphetamine[ note 2 ] (contracted from a lpha - m ethyl ph en et hyl amine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity; it is also used to treat binge eating disorder in the form of its inactive prodrug lisdexamfetamine.
Psychosis risk increases 81% on high-dose amphetamine. For this study, researchers analyzed medical data from adults between the ages of 16 and 35 treated at Mass General Brigham between 2005 and ...
Obetrol, a pharmaceutical mixture of amphetamine and methamphetamine salts, was medically indicatedand marketed for treating obesity, as illustrated in this advertisement from 1970. Amphetamine was first synthesized in 1887 in Germany by Romanian chemist, Lazăr Edeleanu, who named the drug phenylisopropylamine.
Levoamphetamine, similarly to dextroamphetamine, acts as a reuptake inhibitor and releasing agent of norepinephrine and dopamine in vitro. [ 10 ][ 14 ] However, there are differences in potency between the two compounds. [ 10 ][ 14 ] Levoamphetamine is either similar in potency or somewhat more potent in inducing the release of norepinephrine ...
Appearance. This is the list of Schedule II controlled substances in the United States as defined by the Controlled Substances Act. [ 1 ] The following findings are required for substances to be placed in this schedule: [ 2 ] The drug or other substance has a high potential for abuse. The drug or other substance has a currently accepted medical ...