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Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Selective iron deposition in the beta cells of pancreatic islets leads to diabetes [4] [2] due to the distribution of transferrin receptor on the beta cells of islets [3] and in the skin leads to hyperpigmentation.
“Using movements that are too intense can cause bruising, and this is obviously something we want to avoid,” Edyta says. Start near the jawline and work your way up to the cheeks. Repeat until ...
[1] [4] In cases where high doses of elemental iron have been ingested and the patient is exhibiting signs and symptoms of severe systemic iron poisoning, supportive care measures like volume resuscitation and deferoxamine should be initiated immediately. [4] A quick response to iron poisoning can significantly improve clinical outcomes.
Bruise caused by colliding with a handrail, typical of extreme sports such as skateboarding and rollerblading. Bruise caused by a sprained ankle Black eye and subconjunctival hemorrhage after a punch to the face. Bruise shapes may correspond directly to the instrument of injury or be modified by additional factors.
A heated blanket or heating pad might keep you warm in the cold winter months, but experts are warning of a potential danger. Too much close exposure to high heat can cause noticeable skin damage ...
[8] [1] Facial trauma can also result from wartime injuries such as gunshots and blasts. Animal attacks and work-related injuries such as industrial accidents are other causes. [9] Vehicular trauma is one of the leading causes of facial injuries. Trauma commonly occurs when the face strikes a part of the vehicle's interior, such as the steering ...
Before iron deficiency anemia sets in, “the body will do everything it can to retain the right number of red blood cells. So, it will deplete the storage iron before it depletes the red blood ...