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  2. Clostridioides difficile infection - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    C. difficile may colonize the human colon without symptom; approximately 2–5% of the adult population are carriers, although it varies considerably with demographics. [20] The risk of colonization has been linked to a history of unrelated diarrheal illnesses (e.g. laxative abuse and food poisoning due to Salmonellosis or Vibrio cholerae ...

  3. Clostridioides difficile - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile

    [4] [5] It is known also as C. difficile, or C. diff (/ s iː d ɪ f /), and is a Gram-positive species of spore-forming bacteria. [6] Clostridioides spp. are anaerobic, motile bacteria, ubiquitous in nature and especially prevalent in soil. Its vegetative cells are rod-shaped, pleomorphic, and occur in pairs or short chains. Under the ...

  4. List of medical abbreviations: C - Wikipedia

    en.wikipedia.org/wiki/List_of_medical...

    C/C/E: clubbing, cyanosis, and edema (general signs of cardiovascular disease) CCG: Clinical commissioning group: CCF: congestive cardiac failure: CCK: cholecystokinin: CCK-PZ: cholecystokinin-pancreozymin: CCNS: cell cycle–nonspecific [drug] (a type of drug used in chemotherapy) CCOC: clear cell odontogenic carcinoma: CCOT

  5. Tolevamer - Wikipedia

    en.wikipedia.org/wiki/Tolevamer

    Tolevamer was designed to bind the enterotoxins of Clostridioides difficile. Since it has no antibiotic properties, it does not harm the gut flora. Early studies used the sodium salt, but it was soon replaced with the potassium sodium salt to prevent hypokalaemia, which is often associated with diarrhea. [2] [3]

  6. Bezlotoxumab - Wikipedia

    en.wikipedia.org/wiki/Bezlotoxumab

    In June 2016, the Antimicrobial Drugs Advisory Committee of the US Food and Drug Administration [9] voted to recommend approval of Merck's license application for bezlotoxumab by a vote of 10 to 5, generally expressing a willingness to accept that the trials had proven that bezlotoxumab decreased recurrence of C. difficile overall. [10]

  7. Clostridioides difficile toxin A - Wikipedia

    en.wikipedia.org/wiki/Clostridioides_difficile...

    SEM of Clostridioides difficile bacteria PaLoc Reference: Clostridioides difficile strain 630, DSM 27543, genome GenBank accession number AM180355 Positions 770.154 to 789.973 bp, total locus size 19.8 kb. Clostridioides difficile toxin A (TcdA) is a toxin produced by the bacteria Clostridioides difficile, formerly known as Clostridium ...

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