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Mebeverine is used to alleviate some of the symptoms of irritable bowel syndrome (IBS) and related conditions; specifically stomach pain and cramps, persistent diarrhoea, and flatulence. [2] Historically data from controlled clinical trials have not found a difference from placebo or statistically significant results in the global improvement ...
Otilonium bromide is a drug used to treat abdominal pain caused by irritable bowel syndrome. It is an antispasmodic , which is useful to treat the symptoms of irritable bowel syndrome by reducing abdominal spasms ( colic ), bloating, pain, and gut motility.
Pinaverium bromide is a medication used for functional gastrointestinal disorders. It belongs to a drug group called antispasmodics and acts as a calcium channel blocker in helping to restore the normal contraction process of the bowel. It is most effective when taken for a full course of treatment and is not designed for immediate symptom ...
Chlordiazepoxide is an anti-anxiety medication belonging to the benzodiazepine class. [4] Its use in IBS is thought to be due to its calming ability for patients that have IBS symptoms that are worsened by anxiety. Clidinium bromide is a synthetic quaternary ammonium antimuscarinic, [5] a sub-class of a family of drugs known as anticholinergics.
Trimebutine is a drug with antimuscarinic and very weak mu opioid agonist effects. [1] It is used for the treatment of irritable bowel syndrome and other gastrointestinal disorders. The major product from drug metabolism of trimebutine in human beings is nortrimebutine , [ 2 ] which comes from removal of one of the methyl groups attached to the ...
Alosetron, sold under the brand name Lotronex among others, is a 5-HT 3 antagonist used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in females only. It was patented in 1987 and approved for medical use in 2002. [2] It is currently marketed by Prometheus Laboratories Inc. .
Itopride (INN; brand name Ganaton) is a prokinetic benzamide derivative. These drugs inhibit dopamine and acetylcholine esterase enzyme and have a gastrokinetic effect. [3] Itopride is indicated for the treatment of functional dyspepsia and other gastrointestinal conditions. [4] It is a combined D 2 receptor antagonist and acetylcholinesterase ...
Eluxadoline, sold under the brand names Viberzi and Truberzi, [3] is a medication taken by mouth for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). [4] It was approved for use in the United States in 2015. [5] The drug originated from Janssen Pharmaceutica and was ...
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