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  2. Messenger RNA - Wikipedia

    en.wikipedia.org/wiki/Messenger_RNA

    Finally, the mRNA is degraded. In molecular biology, messenger ribonucleic acid (mRNA) is a single-stranded molecule of RNA that corresponds to the genetic sequence of a gene, and is read by a ribosome in the process of synthesizing a protein.

  3. Transcriptome - Wikipedia

    en.wikipedia.org/wiki/Transcriptome

    RNA is the main carrier of genetic information that is responsible for the process of converting DNA into an organism's phenotype. A gene can give rise to a single-stranded messenger RNA (mRNA) through a molecular process known as transcription; this mRNA is complementary to the strand of DNA it originated from. [6]

  4. Primary transcript - Wikipedia

    en.wikipedia.org/wiki/Primary_transcript

    Pre-mRNA is synthesized from a DNA template in the cell nucleus by transcription. Pre-mRNA comprises the bulk of heterogeneous nuclear RNA (hnRNA). Once pre-mRNA has been completely processed, it is termed "mature messenger RNA", or simply "messenger RNA". The term hnRNA is often used as a synonym for pre-mRNA, although, in the strict sense ...

  5. Transcription (biology) - Wikipedia

    en.wikipedia.org/wiki/Transcription_(biology)

    In virology, the term transcription is used when referring to mRNA synthesis from a viral RNA molecule. The genome of many RNA viruses [a] is composed of negative-sense RNA which acts as a template for positive sense viral messenger RNA - a necessary step in the synthesis of viral proteins needed for viral replication.

  6. Adaptor hypothesis - Wikipedia

    en.wikipedia.org/wiki/Adaptor_hypothesis

    The adaptor hypothesis is a theoretical scheme in molecular biology to explain how information encoded in the nucleic acid sequences of messenger RNA (mRNA) is used to specify the amino acids that make up proteins during the process of translation.

  7. Translation (biology) - Wikipedia

    en.wikipedia.org/wiki/Translation_(biology)

    Overview of eukaryotic messenger RNA (mRNA) translation Translation of mRNA and ribosomal protein synthesis Initiation and elongation stages of translation involving RNA nucleobases, the ribosome, transfer RNA, and amino acids The three phases of translation: (1) in initiation, the small ribosomal subunit binds to the RNA strand and the initiator tRNA–amino acid complex binds to the start ...

  8. Protein metabolism - Wikipedia

    en.wikipedia.org/wiki/Protein_metabolism

    Once the RNA reaches a terminator sequence, it dissociates from the DNA template strand and terminates the mRNA sequence as well. Transcription is regulated in the cell via transcription factors. Transcription factors are proteins that bind to regulatory sequences in the DNA strand such as promoter regions or operator regions.

  9. Untranslated region - Wikipedia

    en.wikipedia.org/wiki/Untranslated_region

    DNA is initially transcribed into a messenger RNA (mRNA) molecule. The mRNA is then translated into a protein. (See Central dogma of molecular biology.) mRNA structure, approximately to scale for a human mRNA. In molecular genetics, an untranslated region (or UTR) refers to either of two sections, one on each side of a coding sequence on a ...