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  2. Huntington's disease - Wikipedia

    en.wikipedia.org/wiki/Huntington's_disease

    Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [9] [1] A general lack of coordination and an unsteady gait often follow. [2]

  3. Medical mystery solved: Why do some people develop Huntington ...

    www.aol.com/news/medical-mystery-solved-why...

    Huntington's disease, which affects about 30,000 Americans, is a fatal, inherited disorder that causes progressive movement, psychological and cognitive problems.

  4. Surprise finding sheds light on what causes Huntington's ...

    www.aol.com/news/surprise-finding-sheds-light...

    Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

  5. Chorea - Wikipedia

    en.wikipedia.org/wiki/Chorea

    Huntington's disease is a neurodegenerative disease and most common inherited cause of chorea. The condition was formerly called Huntington's chorea but was renamed because of the important non-choreic features including cognitive decline and behavioural change.

  6. Huntingtin - Wikipedia

    en.wikipedia.org/wiki/Huntingtin

    Huntingtin (Htt) is the protein coded for in humans by the HTT gene, also known as the IT15 ("interesting transcript 15") gene. [5] Mutated HTT is the cause of Huntington's disease (HD), and has been investigated for this role and also for its involvement in long-term memory storage.

  7. Surprise finding sheds light on what causes Huntington's ...

    lite.aol.com/tech/story/0001/20250116/b87b387b4...

    The genetic mutation linked to Huntington's has long been known, but scientists haven't understood how people could have the mutation from birth, but not develop any problems until later in life. New research shows that the mutation is, surprisingly, harmless for decades.

  8. Hyperkinesia - Wikipedia

    en.wikipedia.org/wiki/Hyperkinesia

    Hyperkinesia, more specifically chorea, is the hallmark symptom of Huntington's disease, formerly referred to as Huntington's chorea. Appropriately, chorea is derived from the Greek word, khoros, meaning "dance." The extent of the hyperkinesia exhibited in the disease can vary from solely the little finger to the entire body, resembling ...

  9. Anticipation (genetics) - Wikipedia

    en.wikipedia.org/wiki/Anticipation_(genetics)

    This is the case for Huntington's disease, where the trinucleotide repeat encodes a long stretch of glutamine residues. When the repeat is present in an untranslated region, it could affect the expression of the gene in which the repeat is found (ex. fragile X ) or many genes through a dominant negative effect (ex. myotonic dystrophy ).

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