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The gene encoding IFNα2, the IFNA2 gene, is clustered with all other type I IFN genes on chromosome 9 [8] and as all type I IFN genes, it is devoid of intron. [9] The open reading frame (coding sequence) of IFNA2 codes for a pre-protein of 188 amino acids with a 23 amino acid signal peptide allowing secretion of the mature protein. The mature ...
Interferon alfa or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography.
The ex-dividend date is also a factor in computing U.S. taxes that depend on holding periods. To receive favorable personal income tax rates on qualified dividends of a common stock, the stock must be held continuously for over 60 calendar days within the window of 121 calendar days centered on the ex-dividend date. Otherwise the dividend ...
The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human type I IFNs include many subtypes, such as interferons-α, -β, -ε, -κ, -ω, and -ζ.
The type II IFN (IFN-γ) gene was also isolated around this time. [83] Interferon was first synthesized manually at Rockefeller University in the lab of Dr. Bruce Merrifield, using solid phase peptide synthesis, one amino acid at a time. He later won the Nobel Prize in chemistry.
n/a Ensembl n/a n/a UniProt n a n/a RefSeq (mRNA) n/a n/a RefSeq (protein) n/a n/a Location (UCSC) n/a n/a PubMed search n/a Wikidata View/Edit Human Interferon, type 1, cluster, also known as IFN1@, is a human gene. References ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine. ^ "Entrez Gene: IFN1@ interferon, type 1, cluster ...
IFN of IfN may mean Interferon, a type of signaling proteins; Integrated Flux Nebula, a cloud of gas and dust illuminated by the integrated flux of all the stars in the Milky Way (rather than a single star or group of stars). Leibniz Institute for Neurobiology (Leibniz-Institut für Neurobiologie), Germany; India Fund, Inc., a mutual fund
The human interferon-gamma receptor complex consists the heterodimer of two chains: IFNGR1 and IFNGR2. [2] [3] In unstimulated cells, these subunits are not preassociated with each other but rather associate through their intracellular domains with inactive forms of specific Janus family kinases (Jak1 and Jak2).