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Uterine hyperstimulation or hypertonic uterine dysfunction is a potential complication of labor induction. This is displayed as Uterine tachysystole - the contraction frequency numbering more than five in a 10-minute time frame or as contractions exceeding more than two minutes in duration. [ 1 ]
Ovarian hyperstimulation syndrome (OHSS) is a medical condition that can occur in some women who take fertility medication to stimulate egg growth, and in other women in sporadic cases. Most cases are mild, but rarely the condition is severe and can lead to serious illness or even death.
Uterine Tachysystole is a condition of excessively frequent uterine contractions during pregnancy. [1] It is most often seen in induced or augmented labor , though it can also occur during spontaneous labor , [ 2 ] and this may result in fetal hypoxia and acidosis .
Why does ovarian hyperstimulation syndrome occur? OHSS is a potential side effect of stimulating the ovaries to produce multiple eggs at the same time either during the first part of an IVF cycle ...
When used in conjunction with in vitro fertilization (IVF), controlled ovarian hyperstimulation confers a need to avoid spontaneous ovulation, since oocyte retrieval of the mature egg from the fallopian tube or uterus is much harder than from the ovarian follicle. The main regimens to achieve ovulation suppression are:
Vaginally administered misoprostol had improved outcomes of inducing labor within twenty four hours compared to oxytocin, but was associated with uterine hyperstimulation. [15] Misoprostol is an agonist of EP1 and EP3 receptors, and can cause a greater stimulation at lower concentrations.
Theca lutein cyst is a type of bilateral functional ovarian cyst filled with clear, straw-colored fluid. These cysts result from exaggerated physiological stimulation (hyperreactio luteinalis) due to elevated levels of beta-human chorionic gonadotropin (beta-hCG) or hypersensitivity to beta-hCG.
Controlled ovarian hyperstimulation is generally part of in vitro fertilization, and the aim is generally to develop multiple follicles (optimally between 11 and 14 antral follicles measuring 2–8 mm in diameter), [5] followed by transvaginal oocyte retrieval, co-incubation, followed by embryo transfer of a maximum of two embryos at a time. [6]