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Early OHSS develops before pregnancy testing and late OHSS is seen in early pregnancy. [citation needed] Criteria for severe OHSS include enlarged ovary, ascites, hematocrit > 45%, WBC > 15,000, oliguria, creatinine 1.0–1.5 mg/dl, creatinine clearance > 50 ml/min, liver dysfunction, and anasarca. [4]
OHSS may be caused by “an excess of substances made by the hyperstimulated ovaries that increases leakage of fluid rich in protein out of the blood vessels, where it needs to be, to other spaces ...
Older poor responders have a lower range of pregnancy rates compared with younger ones (1.5–12.7 versus 13.0–35%, respectively). [7] Also, the other way around, there is a lower prevalence of poor responders among young women compared to those of advancing age, with 50% of women aged 43–44 years being poor responders. [5]
The addition of estrogen or hCG as adjunctives to progesterone do not appear to affect outcomes pregnancy rate and live birth rate in IVF. [1] In fact, luteal support with human chorionic gonadotropin (hCG) alone or as a supplement to progesterone has been associated with a higher risk of ovarian hyperstimulation syndrome (OHSS). [2]
The researchers then looked at how being pregnant more than once might affect measures of aging. Women with more pregnancies aged up to five months faster compared to women with fewer pregnancies ...
The data suggested that biological age increased by three per cent more per year in those who have been pregnant, and those with more than one pregnancy were said to age up to five months faster.
Laparoscopic surgery is safe to do during the first half of pregnancy, but risk of uterus and fetus injury increases after 20 weeks of pregnancy. [23] Laparotomy is considered if the cyst is malignant and too large to remove laparoscopically. [26] A laparotomy is preferred during the third trimester of pregnancy. [23]
A 1995 study reported that women age fifty or higher experience similar pregnancy rates after oocyte donation as younger women. They are at equal risk for multiple gestation as younger women. In addition, antenatal complications were experienced by the majority of patients, and that high risk obstetric surveillance and care is vital.