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Co-trimoxazole was claimed to be more effective than either of its components individually in treating bacterial infections, although this was later disputed. [ 29 ] [ 30 ] Pharmacokinetics of co-trimoxazole [ 13 ] [ 3 ]
Cotrimoxazole: This is an antibiotic which incorporates sulphonamides and trimethoprim. It covers a broad spectrum of activity and in dentistry, is often used where there are clear signs and indications of bacterial infection that is sensitive to cotrimoxazole. This is determined by bacteriological sensitivity tests. [11]
The term "medication dentistry" is also referred to as anxiety-free dentistry, relaxation dentistry or comfortable dentistry. This is because most of the patients have feelings of anxiety during even a routine trip to the dentist's office. There are a number of sedation drugs, which can be taken by mouth. They have been developed specifically ...
Wide range of infections; penicillin used for streptococcal infections, syphilis, and Lyme disease: Gastrointestinal upset and diarrhea; Allergy with serious anaphylactic reactions; Brain and kidney damage (rare) Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls ...
Eberhard (2022) [1] published a Cochrane review (systematic review and meta-analysis) which found modest benefit for full mouth disinfection, but the superiority (or otherwise) of the intervention had not at the time of review been conclusively demonstrated. Current recommendations support its use as equal and equivalent to other established ...
Sore mouth; Hyperkalaemia (high blood potassium) Thrombocytopenia (low number of platelets in the blood) Infrequently (0.1–1.0% frequency) Headache; Jaundice;
Angular cheilitis is thought to be a multifactorial disorder of infectious origin, [10] with many local and systemic predisposing factors. [11] The sores in angular cheilitis are often infected with fungi (yeasts), bacteria, or a combination thereof; [8] this may represent a secondary, opportunistic infection by these pathogens.
[1] [2] It is taken orally (swallowed by mouth). [1] Common side effects include nausea, changes in taste, and rash. [1] Rarely it may result in blood problems such as not enough platelets or white blood cells. [1] Trimethoprim may cause sun sensitivity. [1] There is evidence of potential harm during pregnancy in some animals but not humans. [3]
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