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  2. Model for End-Stage Liver Disease - Wikipedia

    en.wikipedia.org/wiki/Model_for_End-Stage_Liver...

    The Model for End-Stage Liver Disease, or MELD, is a scoring system for assessing the severity of chronic liver disease.It was initially developed to predict mortality within three months of surgery in patients who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure, [1] and was subsequently found to be useful in determining prognosis and prioritizing for receipt of ...

  3. Repeatable Battery for the Assessment of Neuropsychological ...

    en.wikipedia.org/wiki/Repeatable_Battery_for_the...

    It was originally introduced in the screening for dementia, but has also found application in other situations, [3] such as hepatic encephalopathy. [ 4 ] References

  4. King's College Criteria - Wikipedia

    en.wikipedia.org/wiki/King's_College_Criteria

    The King's College criteria were described in a seminal publication in 1989 by J.G. O'Grady and colleagues from King's College School of Medicine. [2] 588 patients with acute liver failure who presented to King's College Hospital from 1973 to 1985 were assessed retrospectively to determine if there were particular clinical features or tests that correlated poorly with prognosis.

  5. Hepatic encephalopathy - Wikipedia

    en.wikipedia.org/wiki/Hepatic_encephalopathy

    Hepatic encephalopathy (HE) is an altered level of consciousness as a result of liver failure. [2] Its onset may be gradual or sudden. [ 2 ] Other symptoms may include movement problems, changes in mood , or changes in personality . [ 2 ]

  6. Child–Pugh score - Wikipedia

    en.wikipedia.org/wiki/Child–Pugh_score

    In primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC), some use a modified Child–Pugh score where the bilirubin references are changed to reflect the fact that these diseases feature high conjugated bilirubin levels. The upper limit for 1 point is 68 μmol/L (4 mg/dL) and the upper limit for 2 points is 170 μmol/L (10 ...

  7. Acute liver failure - Wikipedia

    en.wikipedia.org/wiki/Acute_liver_failure

    In ALF, hepatic encephalopathy leads to cerebral edema, coma, brain herniation, and eventually death. Detection of encephalopathy is central to the diagnosis of ALF. It may vary from subtle deficit in higher brain function (e.g. mood, concentration in grade I) to deep coma (grade IV). Patients presenting as acute and hyperacute liver failure ...

  8. Liver failure - Wikipedia

    en.wikipedia.org/wiki/Liver_failure

    The exact definition of "rapid" is somewhat debatable, and different sub-divisions exist, which are based on the time from onset of first hepatic symptoms to onset of encephalopathy. One scheme defines "acute hepatic failure" as the development of encephalopathy within 26 weeks of the onset of any hepatic symptoms.

  9. Alcoholic hepatitis - Wikipedia

    en.wikipedia.org/wiki/Alcoholic_hepatitis

    Corticosteroids: These guidelines suggest that patients with a modified Maddrey's discriminant function score > 32 or hepatic encephalopathy should be considered for treatment with prednisolone 40 mg daily for four weeks followed by a taper. [15] Models such as the Lille Model can be used to monitor for improvement or to consider alternative ...