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  2. Arteriole - Wikipedia

    en.wikipedia.org/wiki/Arteriole

    An arteriole is a small-diameter blood vessel in the microcirculation that extends and branches out from an artery and leads to capillaries. [1] Arterioles have muscular walls (usually only one to two layers of smooth muscle cells) and are the primary site of vascular resistance. The greatest change in blood pressure and velocity of blood flow ...

  3. Blood vessel - Wikipedia

    en.wikipedia.org/wiki/Blood_vessel

    In general, arteries and arterioles transport oxygenated blood from the lungs to the body and its organs, and veins and venules transport deoxygenated blood from the body to the lungs. Blood vessels also circulate blood throughout the circulatory system. Oxygen (bound to hemoglobin in red blood cells) is the most critical nutrient carried by ...

  4. Tunica intima - Wikipedia

    en.wikipedia.org/wiki/Tunica_intima

    The layer also contains fibroblasts, immune cells and smooth muscle cells. [1] Muscular arteries – Endothelial cells Arterioles – A single layer of endothelial cells Veins – Endothelial cells [3] The inner coat consists of: A layer of pavement endothelium, the cells of which are polygonal, oval, or fusiform, and have very distinct round ...

  5. Internal elastic lamina - Wikipedia

    en.wikipedia.org/wiki/Internal_elastic_lamina

    Micrograph showing the internal elastic lamina (thin pink wavy line - image edge mid-left to image edge bottom-centre-left). H&E stain. The internal elastic lamina or internal elastic lamella is a layer of elastic tissue that forms the outermost part of the tunica intima of blood vessels. It separates tunica intima from tunica media.

  6. Juxtaglomerular apparatus - Wikipedia

    en.wikipedia.org/wiki/Juxtaglomerular_apparatus

    Extraglomerular mesangial cells are located in the junction between the afferent and efferent arterioles. These cells have a contractile property similar to vascular smooth muscles and thus play a role in “regulating GFR” by altering the vessel diameter. Renin is also found in these cells. [4]

  7. Vascular smooth muscle - Wikipedia

    en.wikipedia.org/wiki/Vascular_smooth_muscle

    Vascular smooth muscle cells also play important roles during development, e.g. driving osteocyte differentiation from undifferentiated precursors during osteogenesis. [1] Arteries have a great deal more smooth muscle within their walls than veins, thus their greater wall thickness. This is because they have to carry pumped blood away from the ...

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  9. Afferent arterioles - Wikipedia

    en.wikipedia.org/wiki/Afferent_arterioles

    When renal blood flow is reduced (indicating hypotension) or there is a decrease in sodium or chloride ion concentration, the macula densa of the distal tubule releases prostaglandins (mainly PGI2 and PGE2) and nitric oxide, which cause the juxtaglomerular cells lining the afferent arterioles to release renin, activating the renin–angiotensin–aldosterone system, to increase blood pressure ...