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One mg/dL of creatinine equals 88.4 μmol/L. The typical human reference ranges for serum creatinine are 0.5 mg/dL to 1.0 mg/dL (about 45 μmol/L to 90 μmol/L) for women and 0.7 mg/dL to 1.2 mg/dL (60 μmol/L to 110 μmol/L) for men. The significance of a single creatinine value must be interpreted in light of the patient's muscle mass.
At high concentrations [>300 mg/dL(>50 mmol/L)]: headaches, vomiting, fatigue, carbamylation of proteins [2] Creatinine: Possibly affects glucose tolerance and erythrocyte survival [2] Cyanate: Drowsiness and hyperglycemia, carbamylation of proteins and altered protein function due to being a breakdown product of urea [2] Polyols (e.g ...
For the adult male, the normal range is 0.6 to 1.2 mg/dl, or 53 to 106 μmol/L by the kinetic or enzymatic method, and 0.8 to 1.5 mg/dl, or 70 to 133 μmol/L by the older manual Jaffé reaction. For the adult female, with her generally lower muscle mass, the normal range is 0.5 to 1.1 mg/dl, or 44 to 97 μmol/L by the enzymatic method.
One of the measures of kidney function is the glomerular filtration rate (GFR). Other tests that can assess the function of the kidneys include assessment of electrolyte levels such as potassium and phosphate, assessment of acid-base status by the measurement of bicarbonate levels from a vein, and assessment of the full blood count for anaemia.
mg/dL Full blood glucose (fasting) 3.3 [5] 5.6 [5] mmol/L 60 [177] 100 [177] mg/dL Random glucose: 3.9 [178] 7.8 [178] mmol/L 70 [179] 140 [179] mg/dL Lactate (Venous) 4.5 [23] 19.8 [23] mg/dL: 0.5 [180] 2.2 [180] mmol/L: Lactate (Arterial) 4.5 [23] 14.4 [23] mg/dL: 0.5 [180] 1.6 [180] mmol/L: Pyruvate: 300 [23] 900 [23] μg/dL: 34 [181] 102 ...
Hence, an older woman with a serum creatinine of 1.4 mg/dL may actually have a moderately severe chronic kidney disease, whereas a young muscular male can have a normal level of renal function at this serum creatinine level. Creatinine-based equations should be used with caution in cachectic patients and patients with cirrhosis. They often have ...
Urine protein/creatinine ratio is a widely used initial method to estimate daily protein excretion in urine. [1] [2] [3] Since the diagnosis and management of proteinuric renal diseases and the staging of chronic kidney disease depend on accurate identification and quantitation of proteinuria, [4] [1] the implementation of the 24-hour urine collection is the most accurate procedure in practice ...
A creatinine of 0.7 mg/dL is normal for a small frail woman. A level of 2.0 mg/dL would indicate severe kidney disease in the old woman. The more muscle mass you have, and the more you use those muscles, the more more creatinine you should excrete. A frail old woman is expected to have very low creatinine levels.
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