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Dupuytren's contracture of the right little finger. Arrow marks the area of scarring. Typically, Dupuytren's contracture first presents as a thickening or nodule in the palm, which initially can be with or without pain. [11] Later in the disease process, which can be years later, [12] there is increasing loss of range of motion of the affected ...
Dupuytren's contracture Guillaume Dupuytren, Baron Dupuytren ( UK : / ˌ dj uː p w iː ˈ t r æ̃ , dj uː ˈ p w iː t r ɛ n / , [ 1 ] US : / d ə p w iː ˈ t r æ̃ , d ə ˈ p w iː t r ən / , [ 2 ] French: [ɡijom dypɥitʁɛ̃] ; 5 October 1777 – 8 February 1835) was a French anatomist and military surgeon .
Collagenase clostridium histolyticum is an enzyme produced by the bacterium Clostridium histolyticum that dismantles collagen.It is used as a powder-and-solvent injection kit for the treatment of Dupuytren's contracture, a condition where the fingers bend towards the palm and cannot be fully straightened, and Peyronie's disease, a connective tissue disorder involving the growth of fibrous ...
The pain frequently occurs at night and can even radiate to the shoulder. Even though the diagnosis is straightforward, the treatment is surgical decompression of the median nerve after deroofing of the carpal tunnel. [3] Dupuytren's contracture is another disorder of the fingers that is due to thickening of the underlying skin tissues of the ...
Many of these deformities, such as Dupuytren's contracture, swan-neck deformity etc. can be associated with both a chronic, progressive event, or an acute injury; [17] such as boutonnière deformity, which can be caused by trauma, [1] or induced by a chronic condition like rheumatoid arthritis. [20]
In adjunct with surgery, refractory muscle contracture can also be treated with Botulinum toxins A and B; however, the effectiveness of the toxin is slowly lost over time, and most patients need a single treatment to correct muscle contracture over the first few weeks after surgery. [21] Shortening of the surgically lengthened muscle can re-occur.
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