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2. Bone marrow failure - Wikipedia

   en.wikipedia.org/wiki/Bone_marrow_failure

   For those with severe bone marrow failure, the cumulative incidence of resulting stem cell transplantation or death was greater than 70% by individuals 60 years of age. [13] The incidence of bone marrow failure is triphasic: one peak at two to five years during childhood (due to inherited causes), and two peaks in adulthood, between 20 and 25 ...

3. Hematopoietic stem cell transplantation - Wikipedia

   en.wikipedia.org/wiki/Hematopoietic_stem_cell...

   Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood, in order to replicate inside a patient and produce additional normal blood cells.

4. Gene therapy for blood diseases - Wikipedia

   en.wikipedia.org/wiki/Gene_therapy_for_blood...

   Patients in the U.S. suffering from sickle cell disease can now receive targeted gene therapies using hematopoietic stem cells. [6] Hematopoietic stem cells are stem cells which differentiate and give rise to red blood cells, white blood cells and platelets. [7] These therapies involve removing hematopoietic stem cells from the patient and ...

5. Aplastic anemia - Wikipedia

   en.wikipedia.org/wiki/Aplastic_anemia

   Hematopoietic stem cell transplantation is also used, especially for patients under 30 years of age with a related, matched marrow donor. [ 5 ] [ 6 ] Aplastic anemia is known to have caused the deaths of Marie Curie , [ 7 ] Eleanor Roosevelt , [ 8 ] Luana Reyes , and Molly Holzschlag .

6. Congenital amegakaryocytic thrombocytopenia - Wikipedia

   en.wikipedia.org/wiki/Congenital_amegakaryocytic...

   Although hematopoietic stem cell transplantation has been shown to cure Congenital amegakaryocytic thrombocytopenia, the association of early bone marrow aplasia worsens prognosis. About 30% of those with CAMT die from complications of bleeding and a further 20% die from complications associated with hematopoietic stem cell transplantation. [4]

7. List of conditions treated with hematopoietic stem cell ...

   en.wikipedia.org/wiki/List_of_conditions_treated...

   Mucolipidosis II (I-cell disease) Fucosidosis; Aspartylglucosaminuria; Alpha-mannosidosis; Other Wolman disease (acid lipase deficiency) Immunodeficiencies. T-cell deficiencies Ataxia-telangiectasia; DiGeorge syndrome; Combined T- and B-cell deficiencies Severe combined immunodeficiency (SCID), all types; Well-defined syndromes Wiskott ...