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  2. Scleroderma - Wikipedia

    en.wikipedia.org/wiki/Scleroderma

    Scleroderma. Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [ 2][ 6][ 8] The disease can be either localized to the skin or involve other organs, as well. [ 2] Symptoms may include areas of thickened skin, stiffness, feeling tired, and poor blood flow to the ...

  3. Systemic scleroderma - Wikipedia

    en.wikipedia.org/wiki/Systemic_scleroderma

    Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse.

  4. Scleromyositis - Wikipedia

    en.wikipedia.org/wiki/Scleromyositis

    Scleromyositis, is an autoimmune disease (a disease in which the immune system attacks the body). People with scleromyositis have symptoms of both systemic scleroderma and either polymyositis or dermatomyositis, and is therefore considered an overlap syndrome. Although it is a rare disease, it is one of the more common overlap syndromes seen in ...

  5. Morphea - Wikipedia

    en.wikipedia.org/wiki/Morphea

    Morphea is a form of scleroderma that mainly involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, usually with no internal organ involvement. [1] However, in Deep Morphea inflammation and sclerosis can be found in the deep dermis, panniculus, fascia, superficial muscle and bone.

  6. CREST syndrome - Wikipedia

    en.wikipedia.org/wiki/CREST_syndrome

    Rheumatology. CREST syndrome, also known as the limited cutaneous form of systemic sclerosis (lcSSc), is a multisystem connective tissue disorder. The acronym "CREST" refers to the five main features: calcinosis, Raynaud's phenomenon, esophageal dysmotility, sclerodactyly, and telangiectasia. [ 2]

  7. Reynolds syndrome - Wikipedia

    en.wikipedia.org/wiki/Reynolds_syndrome

    Reynolds syndrome. Reynolds syndrome is a rare secondary laminopathy, consisting of the combination of primary biliary cirrhosis and progressive systemic sclerosis. In some patients this syndrome has also been associated with Sjögren's syndrome and hemolytic anemia. Typical clinical features include jaundice, elevated blood levels of alkaline ...

  8. Lichen sclerosus - Wikipedia

    en.wikipedia.org/wiki/Lichen_sclerosus

    Lichen sclerosus ( LS) is a chronic, inflammatory skin disease of unknown cause which can affect any body part of any person but has a strong preference for the genitals (penis, vulva) and is also known as balanitis xerotica obliterans ( BXO) when it affects the penis. Lichen sclerosus is not contagious. There is a well-documented increase of ...

  9. Hyperreflexia - Wikipedia

    en.wikipedia.org/wiki/Hyperreflexia

    Hyperreflexia is overactive or overresponsive bodily reflexes. Examples of this include twitching and spastic tendencies, which indicate disease of the upper motor neurons and the lessening or loss of control ordinarily exerted by higher brain centers of lower neural pathways (disinhibition). Spinal-cord injury is the most common cause of ...

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