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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
Chiral drugs. Chemical compounds that come as mirror-image pairs are referred to by chemists as chiral or handed molecules. [ 1 ] Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that are equimolar (1:1) mixture of enantiomers are called racemic drugs and these are obviously devoid ...
The structure of the molecule of urea is O=C(−NH 2) 2.The urea molecule is planar when in a solid crystal because of sp 2 hybridization of the N orbitals. [8] [9] It is non-planar with C 2 symmetry when in the gas phase [10] or in aqueous solution, [9] with C–N–H and H–N–H bond angles that are intermediate between the trigonal planar angle of 120° and the tetrahedral angle of 109.5°.
Robert Burns Woodward ForMemRS HonFRSE (April 10, 1917 – July 8, 1979) was an American organic chemist.He is considered by many to be the preeminent synthetic organic chemist of the twentieth century, [3] having made many key contributions to the subject, especially in the synthesis of complex natural products and the determination of their molecular structure.
Organoboron chemistry or organoborane chemistry studies organoboron compounds, also called organoboranes. These chemical compounds combine boron and carbon; typically, they are organic derivatives of borane (BH 3), as in the trialkyl boranes. [1][2] Organoboranes and -borates enable many chemical transformations in organic chemistry — most ...
Retrosynthetic analysis. Appearance. Retrosynthetic analysis is a technique for solving problems in the planning of organic syntheses. This is achieved by transforming a target molecule into simpler precursor structures regardless of any potential reactivity/interaction with reagents. Each precursor material is examined using the same method.
v. t. e. Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms. [ 1 ] Study of structure determines their structural formula.
Louis Frederick Fieser (April 7, 1899 – July 25, 1977) was an American organic chemist, professor, and in 1968, professor emeritus at Harvard University.His award-winning research included work on blood-clotting agents including the first synthesis of vitamin K, synthesis and screening of quinones as antimalarial drugs, work with steroids leading to the synthesis of cortisone, and study of ...