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Locoweed (also crazyweed and loco) is a common name in North America for any plant that produces swainsonine, an alkaloid harmful to livestock. Worldwide, swainsonine is produced by a small number of species , most of them in three genera of the flowering plant family Fabaceae : Oxytropis and Astragalus in North America , [ 1 ] and Swainsona in ...
Oxytropis sericea is a species of flowering plant in the legume family known by the common names white locoweed, white point-vetch, whitepoint crazyweed, and silky crazyweed. It is native to western North America from Yukon and British Columbia south through the Pacific Northwest , the Rocky Mountains , and the Great Plains .
The biosynthesis of swainsonine has been investigated in the fungus Rhizoctonia leguminicola, and it initially involves the conversion of lysine into pipecolic acid.The pyrrolidine ring is then formed via retention of the carbon atom of the pipecolate's carboxyl group, as well as the coupling of two more carbon atoms from either acetate or malonate to form a pipecolylacetate.
This plant may look like wildflowers, but it can cause painful rash and blistering. A video of an Iowa resident with the rash explains why.
Other potential symptoms include: nausea and vomiting, a decreased level of consciousness, and breathing difficulties. [2] Symptoms usually begin within 6 hours of taking the medication by mouth. [2] With extended release formulations symptoms may not occur for up to a day. [2] Seizures are rare in adults but in children occur more often. [2]
Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. [9] [10] Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA).
Children under 6 are more likely to be exposed, but a new study finds that fatal poisonings from laundry detergent pods in a recent three-year period were all in adults.
Levofloxacin and other fluoroquinolones have also been widely used for the treatment of uncomplicated community-acquired respiratory and urinary tract infections, indications for which major medical societies generally recommend the use of older, narrower spectrum drugs to avoid fluoroquinolone resistance development.