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  2. Sumatriptan/naproxen - Wikipedia

    en.wikipedia.org/wiki/Sumatriptan/naproxen

    Sumatriptan/naproxen, sold under the brand name Treximet among others, is a fixed-dose combination medication used to treat migraines. [2] It is taken by mouth. [2] It contains sumatriptan, as the succinate, a serotonin 5-hydroxytryptamine (5-HT) 1b/1d receptor agonist (); and naproxen as the sodium salt, a member of the arylacetic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs).

  3. Antimigraine drug - Wikipedia

    en.wikipedia.org/wiki/Antimigraine_drug

    The triptan drug class includes 1st generation sumatriptan (which has poor bioavailability), and second generation zolmitriptan. [2] Due to their safety, efficacy and selectivity, triptans are considered first line agents for abortion of migraines. [2] These medications are selective 5-HT 1B/1D receptor agonists with some activity at 5-HT 1F.

  4. Treatment and management of COVID-19 - Wikipedia

    en.wikipedia.org/wiki/Treatment_and_management...

    This registry based, multi-center, multi-country data provide provisional support for the use of ECMO for COVID-19 associated acute hypoxemic respiratory failure. Given that this is a complex technology that can be resource intense, guidelines exist for the use of ECMO during the COVID-19 pandemic. [85] [86] [87]

  5. Sumatriptan - Wikipedia

    en.wikipedia.org/wiki/Sumatriptan

    Sumatriptan, sold under the brand name Imitrex among others, is a medication used to treat migraine headaches and cluster headaches. [1] It is taken orally , intranasally , or by subcutaneous injection . [ 2 ]

  6. Management of migraine - Wikipedia

    en.wikipedia.org/wiki/Management_of_migraine

    Rescue treatment involves acute symptomatic control with medication. [4] Recommendations for rescue therapy of migraine include: (1) migraine-specific agents such as triptans, CGRP antagonists, or ditans for patients with severe headaches or for headaches that respond poorly to analgesics, (2) non-oral (typically nasal or injection) route of administration for patients with vomiting, (3) avoid ...

  7. Discovery and development of triptans - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The first selective 5-HT 1B/1D agonist, sumatriptan, was first synthesized as a subcutaneous injection, then as an oral tablets and more recently as a nasal spray, it is also available in some countries as suppositories. The subcutaneous injection is the fastest way to stop a rapidly progressing migraine attack.

  8. Triptan - Wikipedia

    en.wikipedia.org/wiki/Triptan

    The patent on Imitrex STATDose expired in December 2006, and injectable sumatriptan became available as a generic formula in August 2008. [citation needed] Sumavel Dosepro is a needle-free delivery of injectable sumatriptan that was approved in the US by the FDA in July 2009. [17] Sumatriptan became available as a generic in the US in late 2009.

  9. WHO Model List of Essential Medicines - Wikipedia

    en.wikipedia.org/wiki/WHO_Model_List_of...

    The WHO Model List of Essential Medicines (aka Essential Medicines List or EML [1]), published by the World Health Organization (WHO), contains the medications considered to be most effective and safe to meet the most important needs in a health system. [2]

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