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Permethrin is a medication and an insecticide. [6] [7] As a medication, it is used to treat scabies and lice. [8]It is applied to the skin as a cream or lotion. [6] As an insecticide, it can be sprayed onto outer clothing or mosquito nets to kill the insects that touch them.
[10] Benzyl benzoate can be a skin irritant when used as a topical scabicide. [7] Overdose can result in blistering and hives or a rash can occur as an allergic reaction. [12] [13] As an excipient in some testosterone-replacement injectable medications, benzyl benzoate has been reported as a cause of anaphylaxis in a case in Australia. [14]
Scabies (/ ˈ s k eɪ b iː z, ˈ s k eɪ b i iː z /; [10] also sometimes known as the seven-year itch) [1] is a contagious human skin infestation by the tiny (0.2–0.45 mm) mite Sarcoptes scabiei, [1] [3] variety hominis.
Effects were also observed in the liver (rats, mice, and dogs), heart (dogs), and thyroid gland (rats). Some effects were also seen in the kidney (mice and rats). However, neurotoxicity was the most sensitive endpoint in the toxicology database, and other effects were generally seen in the presence of neurotoxicity and/or at higher doses.
Bifenthrin is poorly soluble in water and often remains in soil. Its residual half-life in soil is between 7 days and 8 months, depending on the soil type, with a low mobility in most soil types. Bifenthrin has the longest known residual time in soil of insecticides currently on the market. It is a white, waxy solid with a faint sweet smell.
Icaridin, also known as picaridin, is an insect repellent which can be used directly on skin or clothing. [1] It has broad efficacy against various arthropods such as mosquitos, ticks, gnats, flies and fleas, and is almost colorless and odorless.
Cypermethrin is very toxic to cats which cannot tolerate the therapeutic doses for dogs. [6] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses.
DEET is effective against a variety of invertebrates, including ticks, flies, mosquitos, and some parasitic worms. [3]A 2018 systematic review found no consistent performance difference between DEET and icaridin in field studies and concluded that they are equally preferred mosquito repellents, noting that 50% DEET offers longer protection but is not available in some countries.
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