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The median lethal dose (LD 50) is between 15 and 18 g/kg body weight in rats and mice, respectively, five times the LD 50 of table salt (3 g/kg in rats). The use of MSG as a food additive and the natural levels of glutamic acid in foods are not of toxic concern in humans. [ 20 ]
A separate meta-analysis focusing on this sleeping disorder in the elderly mentions that those with more than one physical or psychiatric malady experience it at a 60% higher rate than those with one condition or less. It also notes a higher prevalence of insomnia in women over the age of 50 than their male counterparts. [71]
A new study reveals a shocking potential cause for insomnia.
Over the years, MSG has gotten a bad rap, with many claiming it causes symptoms ranging from headaches to nausea after consumption.
The controversy surrounding the safety of MSG started with the publication of Robert Ho Man Kwok's correspondence letter titled "Chinese-Restaurant Syndrome" in the New England Journal of Medicine on 4 April 1968. [22] [23] In his letter, Kwok suggested several possible causes for symptoms that he experienced before he nominated MSG.
Insomnia can be grouped into primary and secondary, or comorbid, insomnia. [124] [125] [126] Primary insomnia is a sleep disorder not attributable to a medical, psychiatric, or environmental cause. [127] There are three main types of primary insomnia.
EDS can affect the ability to function in family, social, occupational, or other settings. [1] [2] A proper diagnosis of the underlying cause and ultimately treatment of symptoms and/or the underlying cause can help mitigate such complications. [3] According to the National Sleep Foundation, around 20 percent of people experience EDS. [4]
Rates of use were lowest among the youngest age group (those aged 20–39) at about 2%, increased to 6% among those aged 50–59, and reached 7% among those aged 80 and over. More adult women (5%) reported using prescription sleep aids than adult men (3%).
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