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Disaccharidases are glycoside hydrolases, enzymes that break down certain types of sugars called disaccharides into simpler sugars called monosaccharides.In the human body, disaccharidases are made mostly in an area of the small intestine's wall called the brush border, making them members of the group of "brush border enzymes".
Sucrose intolerance can also be caused by irritable bowel syndrome, aging, or small intestine disease (secondary sucrose intolerance). There are specific tests used to help determine if a person has sucrose intolerance. The most accurate test is the enzyme activity determination, which is done by biopsying the small intestine.
With sucrose intolerance, the result of consuming sucrose is excess gas production and often diarrhea and malabsorption. Lactose intolerance is a similar condition that reflects an individual's inability to hydrolyze the disaccharide lactose. Sucrase is secreted by the tips of the villi of the epithelium in the small intestine.
Excessive flatus and abdominal bloating may reflect excessive gas production due to fermentation of unabsorbed carbohydrate, especially among patients with a primary or secondary disaccharidase deficiency, such as lactose intolerance or sucrose intolerance. Malabsorption of dietary nutrients and excessive fluid secretion by inflamed small ...
The glucose tolerance test was first described in 1923 by Jerome W. Conn. [4]The test was based on the previous work in 1913 by A. T. B. Jacobson in determining that carbohydrate ingestion results in blood glucose fluctuations, [5] and the premise (named the Staub-Traugott Phenomenon after its first observers H. Staub in 1921 and K. Traugott in 1922) that a normal patient fed glucose will ...
D-xylose absorption test is a medical test performed to diagnose conditions that present with malabsorption of the proximal small intestine [1] due to defects in the integrity of the gastrointestinal mucosa. [2] D-xylose is a monosaccharide, or simple sugar, that does not require enzymes for digestion prior to absorption. Its absorption ...
PDF documents can also contain display settings, including the page display layout and zoom level in a Viewer Preferences object. Adobe Reader uses these settings to override the user's default settings when opening the document. [43] The free Adobe Reader cannot remove these settings.
The name multiple chemical sensitivity has been criticized, partly because MCS is not a sensitivity in the allergic or immunological meaning of that word. [5] Being more sensitive than average to some chemical exposures (e.g., secondhand smoke) is fairly common. [5] MCS is generally used to refer to more significant disability. [5]
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