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An odontogenic keratocyst is a rare and benign but locally aggressive developmental cyst. It most often affects the posterior mandible and most commonly presents in the third decade of life. [1] Odontogenic keratocysts make up around 19% of jaw cysts. [2] Despite its more common appearance in the bone region, it can affect soft tissue. [3]
Odontogenic cysts are a group of jaw cysts that are formed from tissues involved in odontogenesis (tooth development). Odontogenic cysts are closed sacs, and have a distinct membrane derived from the rest of odontogenic epithelium. It may contain air, fluids, or semi-solid material.
Under microscopes, the cyst looks like an odontogenic keratocyst (also called a Keratocyst odontogenic tumor) whereby the lesions displays a parakeratinized epithelium with palisading basal epithelial cells. The term "Primordial cyst" is considered an outdated term and should be avoided.
The exception to these treatments; is the management of cysts which have a higher rate of recurrence – for example odontogenic keratocysts. Options to reduce the recurrence rate include: curettage post enucleation, Carnoy's solution (treatment of the cavity with a potent fixative) or mandibular resection .
Calcifying odontogenic cyst (COC) is a rare developmental lesion that comes from odontogenic epithelium. [2] It is also known as a calcifying cystic odontogenic tumor , which is a proliferation of odontogenic epithelium and scattered nest of ghost cells and calcifications that may form the lining of a cyst , or present as a solid mass.
A glandular odontogenic cyst (GOC) is a rare and usually benign odontogenic cyst developed at the odontogenic epithelium of the mandible or maxilla. [2] [8] [9] [10] Originally, the cyst was labeled as "sialo-odontogenic cyst" in 1987. [7] However, the World Health Organization (WHO) decided to adopt the medical expression "glandular ...
Relative incidence of odontogenic cysts. [14] Periapical cysts are labeled at left. Periapical cysts comprise approximately 75% of the types of cysts found in the oral region. The ratio of individuals diagnosed with periapical cysts is 3:2 male to female, as well as individuals between 20 and 60 years old. Periapical cysts occur worldwide.
The developmental origin has been disputed. Today, most literature agree based on overwhelming evidence that the cyst is predominantly of tooth origin (odontogenic), demonstrating findings consistent with periapical cysts, odontogenic keratocysts or lateral periodontal cysts. [1]