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Flavin mononucleotide (FMN), or riboflavin-5′-phosphate, is a biomolecule produced from riboflavin (vitamin B 2) by the enzyme riboflavin kinase and functions as the prosthetic group of various oxidoreductases, including NADH dehydrogenase, as well as a cofactor in biological blue-light photo receptors. [1]
Riboflavin, also known as vitamin B 2, is a water-soluble vitamin and is one of the B vitamins. [3] [4] [5] Unlike folate and vitamin B 6, which occur in several chemically related forms known as vitamers, riboflavin is only one chemical compound.
In enzymology, a riboflavin phosphotransferase (EC 2.7.1.42) is an enzyme that catalyzes the chemical reaction. alpha-D-glucose 1-phosphate + riboflavin D-glucose + FMN. Thus, the two substrates of this enzyme are alpha-D-glucose 1-phosphate and riboflavin, whereas its two products are D-glucose and FMN.
No evidence of toxicity based on limited human and animal studies. The only evidence of adverse effects associated with riboflavin comes from in vitro studies showing the production of reactive oxygen species (free radicals) when riboflavin was exposed to intense visible and UV light. [23] Vitamin B 3: US UL = 35 mg as a dietary supplement [24]
The enzyme FAD-AMP lyase (cyclizing) (EC 4.6.1.15) catalyzes the reaction . FAD AMP + riboflavin cyclic-4′,5′--phosphate. This enzyme belongs to the family of lyases, specifically the class of phosphorus-oxygen lyases.
Treatment with riboflavin, 5-formyltetrahydrofolate (Folinic acid) and/or L-5-methyltetrahydrofolate (5-MTHF) may lead to a drastic improvement of symptoms. Pyridoxal - 5 - Phosphate (P5P) , a cofactor for the enzyme Serine hydroxymethyltransferase , may also assist with the conversion of tetrahydrofolate (THF) to 5,10-Methylenetetrahydrofolate ...
Many multivitamin formulas contain vitamin C, B 1, B 2, B 3, B 5, B 6, B 7, B 9, B 12, A, E, D 2 (or D 3), K, potassium, iodine, selenium, borate, zinc, calcium, magnesium, manganese, molybdenum, beta carotene, and/or iron. Multivitamins are typically available in a variety of formulas based on age and sex, or (as in prenatal vitamins) based on ...
Adenine is bound to a cyclic ribose at the 1' carbon, while phosphate is bound to the ribose at the 5' carbon to form the adenine nucledotide. Riboflavin is formed by a carbon-nitrogen (C-N) bond between the isoalloxazine and the ribitol. The phosphate group is then bound to the terminal ribose carbon, forming a FMN.
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