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Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
Dose de-escalation below the starting doses in case of poor patient's chemotherapy tolerability applies to cyclophosphamide only. If the nadir ANC > 500/μL, then the doses of etoposide, doxorubicin, and cyclophosphamide for the next cycle are all increased by 20% over the doses used in the previous cycle.
Bendamustine is a white, water-soluble microcrystalline powder with amphoteric properties. It acts as an alkylating agent causing intra-strand and inter-strand cross-links between DNA bases. After intravenous infusion it is extensively metabolised in the liver by cytochrome p450 .
In a medicine that is administered periodically, the trough level should be measured just before the administration of the next dose in order to avoid overdosing. [3] A trough level is contrasted with a "peak level" ( C max ), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time.
Water towers are used to store water at a height sufficient to pressurize a water supply distribution system. Public water system is a regulatory term used in the United States and Canada, referring to specific utilities and organizations providing drinking water.
The treatment starts with an infusion of rituximab. This may be followed by an administration of indium-111 labeled ibritumomab tiuxetan ( 111 In replaces the 90 Y component) to allow the distribution of the medication to be imaged on a gamma camera , before the actual therapy is administered.
Under the Act, the need to add fluoride to a water supply is assessed by a fluoridation committee, which then provides a recommendation to the Health Minister. The Health Minister may then choose to direct the water authority to add fluoride to the water. The first town in Australia to fluoridate its water supply was Beaconsfield, Tasmania in 1953.
Coagulation-flocculation process in a water treatment system. In water treatment, coagulation and flocculation involve the addition of compounds that promote the clumping of fine floc into larger floc so that they can be more easily separated from the water. Coagulation is a chemical process that involves neutralization of charge whereas ...