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Piperazine is freely soluble in water and ethylene glycol, but insoluble in diethyl ether. It is a weak base with two pK b of 5.35 and 9.73 at 25 °C.; the pH of a 10% aqueous solution of piperazine is 10.8–11.8. Piperazine readily absorbs water and carbon dioxide from the air.
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Higher doses are used for anesthesia in combination with other drugs such as xylazine, tiletamine and zolazepam. Azaperone is also used in combination with strong narcotics such as etorphine or carfentanil for tranquilizing large animals such as elephants. [2] Use in horses is avoided as adverse reactions may occur.
Some are used as recreational drugs and some are used in scientific research. [2] List of substituted piperazines ... ORG-12962 (1-(5-trifluoromethyl-6-chloropyridin ...
Chemical nomenclature, replete as it is with compounds with very complex names, is a repository for some names that may be considered unusual. A browse through the Physical Constants of Organic Compounds in the CRC Handbook of Chemistry and Physics (a fundamental resource) will reveal not just the whimsical work of chemists, but the sometimes peculiar compound names that occur as the ...
Quipazine produces a head-twitch response and other psychedelic-consistent effects in animal studies including in mice, rats, and monkeys. [ 1 ] [ 3 ] [ 9 ] [ 10 ] [ 11 ] These effects appear to be mediated by activation of the serotonin 5-HT 2A receptor, as they are blocked by serotonin 5-HT 2A receptor antagonists like ketanserin .
pentobarbital – humane euthanasia of animals not to be used for food; pentoxyfylline – xanthine derivative used in as an antiinflammatory drug and in the prevention of endotoxemia; pergolide – dopamine receptor agonist used for the treatment of pituitary pars intermedia dysfunction in horses; phenobarbital – anti-convulsant used for ...
1-(2-Pyridinyl)piperazine is a chemical compound and piperazine derivative. Some derivatives of this substance are known to act as potent and selective α 2-adrenergic receptor antagonists, such as 1-(3-fluoro-2-pyridinyl)piperazine. [1] A few pyridinylpiperazine derivatives are drugs, including: Azaperone — antipsychotic; Atevirdine ...