Search results
Results from the WOW.Com Content Network
6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [ 1 ] [ 2 ] It is the 6- methoxy derivative of the serotonergic psychedelic N , N -dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5-MeO-DMT .
N,N-Dimethyltryptamine (DMT or N,N-DMT) is a substituted tryptamine that occurs in many plants and animals, including humans, and which is both a derivative and a structural analog of tryptamine. [1] [2] [3] DMT is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. [9]
NBoc-DMT, or NB-DMT, also known as N1-tert-butoxycarbonyl-N,N-dimethyltryptamine, is a serotonergic psychedelic of the tryptamine family. [ 1 ] [ 2 ] It is a novel designer and recreational drug and is a synthetic modification of dimethyltryptamine (DMT) with an N′ - tert -butyloxycarbonyl (NBoc) group .
Post-mortem chemistry, also called necrochemistry or death chemistry, is a subdiscipline of chemistry in which the chemical structures, reactions, processes and parameters of a dead organism is investigated. Post-mortem chemistry plays a significant role in forensic pathology.
Exocytosis is the process by which a large amount of molecules are released; thus it is a form of bulk transport. Exocytosis occurs via secretory portals at the cell plasma membrane called porosomes. Porosomes are permanent cup-shaped lipoprotein structures at the cell plasma membrane, where secretory vesicles transiently dock and fuse to ...
The lack of tolerance development with 5-MeO-DMT may be due to biased agonism of the serotonin 5-HT 2A receptor. [5] More specifically, 5-MeO-DMT activates the G q signaling pathway of the serotonin 5-HT 2A receptor with much less potency in recruiting β-arrestin2. [5] [22] Activation of β-arrestin2 is linked to receptor downregulation and ...
Psilocin, also known as 4-hydroxy-N,N-dimethyltryptamine (4-OH-DMT), is a substituted tryptamine alkaloid and a serotonergic psychedelic. It is present in most psychedelic mushrooms [ 7 ] together with its phosphorylated counterpart psilocybin .
Bufotenin, also known as 5-hydroxy-N,N-dimethyltryptamine (5-HO-DMT), is a substituted tryptamine and a derivative of dimethyltryptamine (DMT; N,N-dimethyltryptamine) and serotonin (5-hydroxytryptamine; 5-HT). It is also closely related to psilocin (4-HO-DMT) and 5-MeO-DMT. The predicted log P of bufotenin ranges from 0.89 to 2.04.