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Pincus notes, “An older, but important meta-analysis of 28 studies showed a 73% increased risk of all type dementia, 56% increase of Alzheimer’s Disease, and 127% increase of vascular dementia ...
Frailty can have various symptoms including muscle weakness (reduced grip strength), slower walking speed, exhaustion, unintentional weight loss, and frequent falls. [ 3 ] [ 4 ] Older people with certain medical conditions such as diabetes , heart disease and dementia , are also more likely to have frailty.
The prevention of dementia involves reducing the number of risk factors for the development of dementia, and is a global health priority needing a global response. [1] [2] Initiatives include the establishment of the International Research Network on Dementia Prevention (IRNDP) [3] which aims to link researchers in this field globally, and the establishment of the Global Dementia Observatory ...
Sarcopenia (ICD-10-CM code M62.84 [1]) is a type of muscle loss that occurs with aging and/or immobility. It is characterized by the degenerative loss of skeletal muscle mass, quality, and strength. The rate of muscle loss is dependent on exercise level, co-morbidities, nutrition and other factors.
People who have had stomach surgery for weight loss, older adults, and people with gastrointestinal conditions like Crohn’s disease and celiac disease are also at risk for a B12 deficiency, she ...
Inflammation of the jejunum or ileum can prevent nutrient absorption, leading to pellagra, and this can in turn be caused by Crohn's disease. [10] Gastroenterostomy can also cause pellagra. [ 10 ] Chronic alcoholism can also cause poor absorption, which combined with a diet already low in niacin and tryptophan produces pellagra. [ 10 ]
The study helps further lay to rest concerns that treatment with semaglutide - originally designed for type 2 diabetes but now also approved for weight loss under the brand Wegovy - increases the ...
Inflammaging is thought to be caused by a loss of control over systemic inflammation resulting in chronic overstimulation of the innate immune system. Inflammaging is a significant risk factor in mortality and morbidity in aged individuals. [2] [3] [4] Inflammation is essential to protect against viral and bacterial infection, as well as ...