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IgA vasculitis (HSP), previously known as Henoch–Schönlein purpura, is an autoimmune disease that most commonly affects children. In the skin, the disease causes palpable purpura (small, raised areas of bleeding underneath the skin), often with joint pain and abdominal pain .
The selection and use of essential medicines: report of the WHO Expert Committee, 2017 (including the 20th WHO Model List of Essential Medicines and the 6th Model List of Essential Medicines for Children). Geneva: World Health Organization. hdl: 10665/259481. ISBN 978-92-4-121015-7. ISSN 0512-3054. WHO technical report series; no. 1006.
Administration of anti-inflammatory medications (such as steroids or NSAIDs) to reduce active inflammation in the kidney. [ 43 ] If the patient is showing signs of kidney failure or end-organ damage , the treatment team may opt to utilize kidney dialysis temporarily (or permanently, in some severe cases) to decrease stress on the kidneys and ...
In adults, there are numerous potential causes, which makes an early kidney biopsy necessary to determine the correct diagnosis and treatment plan. [4] It also differs from the nephrotic syndrome that often develops in young individuals with childhood-onset systemic lupus erythematosus , i.e., cSLE. cSLE is a form of systemic lupus ...
The term over-the-counter (OTC) refers to a medication that can be purchased without a medical prescription. [3] In contrast, prescription drugs require a prescription from a doctor or other health care professional and should only be used by the prescribed individual. [4]
Lithium is approved by the FDA for the treatment of bipolar disorder and is widely prescribed off-label as a treatment for major depressive disorder, [12] often as an augmentation agent. Lithium is recommended for the treatment of schizophrenic disorders only after other antipsychotics have failed; it has limited effectiveness when used alone. [13]
The scarring of the small blood vessels, called capillary sclerosis, is the initial lesion of analgesic nephropathy. [7] Found in the renal pelvis, ureter, and capillaries supplying the nephrons, capillary sclerosis is thought to lead to renal papillary necrosis and, in turn, chronic interstitial nephritis.
Treatment of DPGN depends on the severity of the disease. An optimal treatment for DPGN is immunosuppressive therapy. [11] Two common immunosuppressive drugs used to treat DPGN are cyclophosphamide (CYC) and mycophenolate mofetil (MMF) if the DPGN is caused by SLE. [12] CYC and MMF both preserve the renal function in patients with SLE and DPGN ...