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  2. Tirzepatide - Wikipedia

    en.wikipedia.org/wiki/Tirzepatide

    Tirzepatide has demonstrated significant benefits in obese patients with a common type of heart failure, preserved ejection fraction (HFpEF) in a phase III trial. [ 24 ] [ 25 ] Over two years, tirzepatide reduced the risk of major complications, including urgent heart failure visits, hospitalizations, increased diuretic treatment, and ...

  3. Lisinopril/hydrochlorothiazide - Wikipedia

    en.wikipedia.org/wiki/Lisinopril/hydrochlorothiazide

    Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). [2]

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    Preliminary trial results found a greater weight loss compared to either medication alone. HbA1c was significantly improved compared to cagrilintide alone and non-significantly better than semaglutide alone. [1] [2] In a Phase II trial, weight loss averaged -15.6 percent after 32 weeks, making CagriSema comparable in efficacy to tirzepatide.

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  9. Lisinopril - Wikipedia

    en.wikipedia.org/wiki/Lisinopril

    Zeneca's marketing and brand name, "Zestril", turned out to be stronger than Merck's effort. [28] The drug became a blockbuster for AstraZeneca (formed in 1998), with annual sales in 1999 of $1.2B. [29] The US patents expired in 2002. [29]

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