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Becker's nevus and supernumerary nipples can usually be diagnosed by visually observing the skin. [24] However, if visual observation alone is insufficient to make a conclusive diagnosis, a skin biopsy can be performed. A small sample of skin can be removed from the nevus and examined under a microscope to analyze the cellular components.
Of the nine melanomas, five were in the same body area as the Becker's nevus, with only one occurring within the nevus itself. As this was apparently the first documented co-occurrence of the two diseases, there is so far no evidence of higher malignancy rates in Becker's nevi versus normal skin.
Alfred Blaschko, a private practice dermatologist from Berlin, first described and drew the patterns of the lines of Blaschko in 1901. He obtained his data by studying over 140 patients with various nevoid and acquired skin diseases and transposed the visible patterns the diseases followed onto dolls and statues, then compiled the patterns onto a composite schematic of the human body.
Nevus (pl.: nevi) is a nonspecific medical term for a visible, circumscribed, chronic lesion of the skin or mucosa. [1] The term originates from nævus , which is Latin for " birthmark "; however, a nevus can be either congenital (present at birth) or acquired.
A 13-year-old with a giant congenital melanocytic nevus, or "bathing trunk" Neurocutaneous melanosis is a congenital disorder characterized by the presence of congenital melanocytic nevi on the skin and melanocytic tumors in the leptomeninges of the central nervous system . [ 2 ]
Nevus cells are a variant of melanocytes. [1]: 684 They are larger than typical melanocytes, do not have dendrites, and have more abundant cytoplasm with coarse granules. [2] They are usually located at the dermoepidermal junction or in the dermis of the skin. Dermal nevus cells can be further classified: type A (epithelioid) dermal nevus cells ...
However, a melanocytic nevus is benign, and melanoma is malignant. Most melanocytic nevi never evolve into a cancer, with the lifetime risk for an individual nevus being 1 in 3000 for men and 1 in 11 000 for women. [5] Moreover, dermatologists have a standardized system for determining whether a skin lesion is suspicious for malignant melanoma.
Phakomatosis pigmentokeratotica is a rare neurocutanous condition characterized by the combination of an organoid sebaceous nevus and speckled lentiginous nevus. [1]: 634–5 [2]: 776 It is an unusual variant of epidermal naevus syndrome. [3] It was first described by Happle et al. [4]