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neglected squamous cell carcinoma skin of scalp Advanced squamous cell carcinoma, excision specimen. Note invasion subcutaneous tissue. Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma.
Squamous-cell carcinoma (SCC), also known as epidermoid carcinoma, comprises a number of different types of cancer that begin in squamous cells. [1] These cells form on the surface of the skin, on the lining of hollow organs in the body, and on the lining of the respiratory and digestive tracts .
Frequently reported and reclassified over the last century, keratoacanthoma can be divided into various subtypes and despite being considered benign, their unpredictable behaviour has warranted the same attention as with squamous cell carcinoma. [1] Keratoacanthomas may be divided into the following types: [9]: 763–764 [10]: 643–646
Actinic keratosis (AK), sometimes called solar keratosis or senile keratosis, [1] [2] is a pre-cancerous [3] area of thick, scaly, or crusty skin. [4] [5] Actinic keratosis is a disorder of epidermal keratinocytes that is induced by ultraviolet (UV) light exposure ().
Of nonmelanoma skin cancers, about 80% are basal-cell cancers and 20% squamous-cell skin cancers. [14] Basal-cell and squamous-cell skin cancers rarely result in death. [6] In the United States, they were the cause of less than 0.1% of all cancer deaths. [1] Globally in 2012, melanoma occurred in 232,000 people and resulted in 55,000 deaths. [6]
Cock's peculiar tumour is a sebaceous cyst linked growth that can resemble a squamous cell carcinoma. [1] The name is given after a 19th-century English surgeon Edward Cock . [ 2 ] The proliferating cyst is usually solitary, but it often arises from a simple trichilemmal cysts in the hair follicle epithelium and these are multiple in 70% of cases.
Primary cutaneous adenoid cystic carcinoma is a cutaneous condition characterized by a tumor that usually presents on the chest, scalp, or vulva of middle- to older-aged persons. [1]: 670 Primary cutaneous adenoid cystic carcinomas have been misinterpreted as metastatic lesions. [2] It was characterized in 1975. [3]
Erosive pustular dermatitis of the scalp presents with pustules, erosions, and crusts on the scalp of primarily older Caucasian females, and on biopsy, has a lymphoplasmacytic infiltrate with or without foreign body giant cells and pilosebaceous atrophy. [2]: 650 [3]: 761 The exact cause of erosive pustular dermatitis of the scalp is unknown.