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6% (< 60 years old), 20% (> 60 years old) [4] Vitamin B12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
The relationship to vitamin B12 deficiency has been the subject of many studies. Although these studies found that 0–42% of those with recurrent ulcers have a vitamin B12 deficiency, an association with deficiency is rare. Even in the absence of deficiency, vitamin B12 supplementation may be helpful due to unclear mechanisms. [18]
Groups most at risk of B12 deficiency. Older adults over the age of 60 because the ... treatment. Treatment of B12 deficiency generally depends on the severity of the deficiency and what is ...
One of the superpowers of vitamin B12 is that it is the only water-soluble vitamin that can be stored in the human body, Kitchens points out, and it can remain stored in the liver for several years.
Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says.
Pernicious anemia due to autoimmune problems occurs in about one per 1000 people in the US. Among those over the age of 60, about 2% have the condition. [8] It more commonly affects people of northern European descent. [2] Women are more commonly affected than men. [15] With proper treatment, most people live normal lives. [5]
Vitamin B12, also known as cobalamin, is a water-soluble vitamin involved in metabolism. [2] It is one of eight B vitamins. It is required by animals, which use it as a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. [3]
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