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Swiss-model pipeline comprises the four main steps that are involved in building a homology model of a given protein structure: Identify structural template (s). BLAST and HHblits are used to identify templates. Those are stored in the Swiss-model Template Library (SMTL), which is derived from Protein Data Bank (PDB). Align target sequence and template structure (s). Build model and minimize ...
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves activation, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin.
Factor V. Coagulation factor V (Factor V), also less commonly known as proaccelerin or labile factor, is a protein involved in coagulation, encoded, in humans, by F5 gene. [5] In contrast to most other coagulation factors, it is not enzymatically active but functions as a cofactor. [5] Factor V deficiency leads to predisposition for hemorrhage ...
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The operator, K, is known as the coagulation kernel and describes the rate at which particles of size coagulate with particles of size . Analytic solutions to the equation exist when the kernel takes one of three simple forms: known as the constant, additive, and multiplicative kernels respectively. [7] For the case it could be mathematically proven that the solution of Smoluchowski ...
Activated clotting time (ACT), also known as activated coagulation time, is a test of coagulation. [1][2] The ACT test can be used to monitor anticoagulation effects, such as from high-dose heparin before, during, and shortly after procedures that require intense anticoagulant administration, such as cardiac bypass, interventional cardiology ...
Tissue factor, also called platelet tissue factor or Coagulation factor III, [5] is a protein present in subendothelial tissue and leukocytes which plays a major role in coagulation and, in humans, is encoded by F3 gene.