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  2. Semax - Wikipedia

    en.wikipedia.org/wiki/Semax

    A 2018 study involving 110 patients recovering from ischemic stroke reported increases in brain-derived neurotrophic factor (BDNF) (correlated with early rehabilitation) in patients administered Semax. [15] In another 2018 study involving 24 healthy participants, Semax was shown to increase fMRI default mode network activity relative to placebo ...

  3. Brain-derived neurotrophic factor - Wikipedia

    en.wikipedia.org/wiki/Brain-derived_neurotrophic...

    Brain-derived neurotrophic factor (BDNF), or abrineurin, [5] is a protein [6] that, in humans, is encoded by the BDNF gene. [ 7 ] [ 8 ] BDNF is a member of the neurotrophin family of growth factors, which are related to the canonical nerve growth factor (NGF), a family which also includes NT-3 and NT-4 /NT-5.

  4. Cerebrolysin - Wikipedia

    en.wikipedia.org/wiki/Cerebrolysin

    Cerebrolysin (developmental code name FPF-1070) is an experimental mixture of enzymatically-treated peptides derived from pig brain whose constituents can include brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), nerve growth factor (NGF), and ciliary neurotrophic factor (CNTF).

  5. N-Phenylacetyl-L-prolylglycine ethyl ester - Wikipedia

    en.wikipedia.org/wiki/N-Phenylacetyl-L...

    N-Phenylacetyl-l-prolylglycine ethyl ester is promoted as a nootropic and is a prodrug of cyclic glycine-proline. [a] [2] Other names include the brand name Noopept (Russian: Ноопепт), developmental code GVS-111, and proposed INN omberacetam.

  6. ALTO-100 - Wikipedia

    en.wikipedia.org/wiki/ALTO-100

    ALTO-100, previously known as NSI-189 (NeuralStem Inc. 189), [3] is a drug described as a hippocampal neurogenesis stimulant and indirect brain-derived neurotrophic factor (BDNF) modulator which is under development for the treatment of major depressive disorder (MDD), bipolar depression, and post-traumatic stress disorder (PTSD).

  7. Phenylpiracetam - Wikipedia

    en.wikipedia.org/wiki/Phenylpiracetam

    Phenylpiracetam, also known as fonturacetam (INN Tooltip International nonproprietary name) and sold under the brand names Phenotropil, Actitropil, and Carphedon among others, is a stimulant and nootropic medication used in Russia and certain other Eastern European countries in the treatment of cerebrovascular deficiency, depression, apathy, and attention, and memory problems, among other ...

  8. Eutropoflavin - Wikipedia

    en.wikipedia.org/wiki/Eutropoflavin

    Eutropoflavin (4'-Dimethylamino-7,8-dihydroxyflavone) is a synthetic flavone and selective small-molecule agonist of TrkB, the main receptor of brain-derived neurotrophic factor (BDNF), which was derived from structural modification of tropoflavin (7,8-DHF).

  9. Histone deacetylase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Histone_deacetylase_inhibitor

    To carry out gene expression, a cell must control the coiling and uncoiling of DNA around histones.This is accomplished with the assistance of histone acetyl transferases (HAT), which acetylate the lysine residues in core histones leading to a less compact and more transcriptionally active euchromatin, and, on the converse, the actions of histone deacetylases (HDAC), which remove the acetyl ...

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