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Drugs or pharmaceutical agents inducing ototoxicity are regarded as ototoxic medications. Anatomy of the human ear There is a wide range of ototoxic medications, for example, antibiotics , antimalarials , chemotherapeutic agents , non-steroidal anti-inflammatory drugs (NSAIDs) and loop diuretics . [ 2 ]
Ototoxicity is the property of being toxic to the ear (oto-), specifically the cochlea or auditory nerve and sometimes the vestibular system, for example, as a side effect of a drug. The effects of ototoxicity can be reversible and temporary, or irreversible and permanent. It has been recognized since the 19th century. [1]
Some over-the-counter as well as prescription drugs and certain industrial chemicals are ototoxic. Exposure to these can result in temporary or permanent hearing loss. Some medications cause irreversible damage to the ear, and are limited in their use for this reason. The most important group is the aminoglycosides (main member gentamicin). A ...
In addition to medications, hearing loss can also result from specific chemicals in the environment: metals, such as lead; solvents, such as toluene (found in crude oil, gasoline, [44] and automobile exhaust, [44] for example); and asphyxiants. [45] Combined with noise, these ototoxic chemicals have an additive effect on a person's hearing loss ...
Category for ototoxicity. ... Alcohol (drug) P. Pharmacology of ethanol This page was last edited on 27 August 2019, at 15:03 (UTC). Text is available under the ...
Serious side effects include ringing in the ears or loss of hearing, toxicity to kidneys, and allergic reactions to the drug. [11] Ototoxicity is a common quality among aminoglycosides, and its rate of incidence in kanamycin is around 3-10%. [12] Other side effects include: [9] Gastrointestinal effects Nausea, vomiting, diarrhea ...
The Food and Drug Administration doesn’t approve or authorize all pulse oximeters on the market. Devices marketed for “general wellness” among hikers, cyclists or other athletes who might ...
IDPN (3,3'-iminodipropanenitrile) is a neurotoxin with ototoxic and hepatotoxic effects. It causes irreversible movement disorder. It causes irreversible movement disorder. [ 1 ] [ 2 ] [ 3 ]