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Chromium(III) nicotinate is an ionic substance used for chromium supplementation in some nutritional products, where it is also referred to as chromium polynicotinate. It appears in products that are referred to as a medical food used for nutritional support for conditions associated with diabetes mellitus type 2 .
Chromium(III) picolinate (also trivalent chromium) is a chemical compound with the formula Cr(C 5 H 4 N(CO 2)) 3, commonly abbreviated as CrPic 3. It is a bright-red coordination compound derived from chromium (III) and picolinic acid .
One, limited to chromium picolinate, a common supplement ingredient, reported a statistically significant −1.1 kg (2.4 lb) weight loss in trials longer than 12 weeks. [134] The other included all chromium compounds and reported a statistically significant −0.50 kg (1.1 lb) weight change. [ 135 ]
Picolinic acid is an organic compound with the formula NC 5 H 4 CO 2 H.It is a derivative of pyridine with a carboxylic acid (COOH) substituent at the 2-position. It is an isomer of nicotinic acid and isonicotinic acid, which have the carboxyl side chain at the 3- and 4-positions, respectively.
The potential value and toxicity of chromium picolinate as a nutritional supplement, weight loss agent and muscle development agent. Sports Med. 2003;33(3):213-30. However, over a decade of human studies with Cr(pic)(3) indicate that the supplement has not demonstrated effects on the body composition of healthy individuals, even when taken in ...
One of the intracellular proteins influencing the insulin receptor is the oligopeptide apolipoprotein, low molecular weight, chromium-binding substance (apo-chromomodulin) [2]. In vitro, this peptide has the ability to increase tyrosine kinase activity eightfold, depending on the chromium concentration [3]. This in turn promotes insulin ...
It is believed to stimulate the phosphorylation of the 3 tyrosine residues of the β subunits of the insulin receptor. [7] [8] [10] [11] From electronic studies, the crystal field stabilization energy was determined to be 1.74 x 10 3 while the Racah parameter B was 847 cm −1. This indicates that chromium binds to chromodulin in the trivalent ...
Trivalent chromium, or chromium(III), is an essential trace mineral in the human diet. [3] In some nutritional supplements, chromium(III) occurs as chromium(III) picolinate (in which chromium is bound to picolinic acid) or chromium(III) nicotinate (in which chromium is bound to nicotinic acid). Nicotinic acid is also known as the B vitamin niacin.
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